Key takeaways
Evotaz (atazanavir/cobicistat) and Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate) are both medications used to treat HIV, but they have some key differences. Evotaz is a combination of two drugs: atazanavir, a protease inhibitor, and cobicistat, a booster. It must be taken with other HIV medications to form a complete treatment regimen. On the other hand, Stribild is a single-tablet regimen that includes four drugs: elvitegravir, an integrase inhibitor, emtricitabine and tenofovir, both nucleoside reverse transcriptase inhibitors (NRTIs), and cobicistat. This means you can take Stribild alone for HIV treatment. Both medications need to be taken with food, but Stribild is not recommended for people with kidney or liver problems, while Evotaz can be used with caution in these cases. Additionally, Stribild can cause bone problems and is not a good option for pregnant individuals, whereas Evotaz can cause jaundice and is also not recommended during pregnancy. Both medications interact with many other drugs, so it's important to discuss all your medications with your healthcare provider.
