Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Evotaz (atazanavir/cobicistat) and Triumeq (abacavir/dolutegravir/lamivudine) are both medications used to treat HIV, but they have some key differences. Evotaz is a combination of two drugs: atazanavir, a protease inhibitor, and cobicistat, a booster that helps maintain higher levels of atazanavir in your blood. It must be taken with other HIV medications and always with food. On the other hand, Triumeq is a single-tablet regimen that combines three drugs: abacavir and lamivudine, both nucleoside reverse transcriptase inhibitors (NRTIs), and dolutegravir, an integrase inhibitor. Triumeq can be taken with or without food and is a complete treatment on its own. Before starting Triumeq, you need a genetic test to check for a specific trait that could cause a severe allergic reaction, which is not required for Evotaz. Additionally, Triumeq is available in a dissolvable tablet form for children, while Evotaz is only available as a standard tablet. Both medications have their own sets of side effects and interactions, so it's important to discuss with your healthcare provider which option is best for you.
Evotaz (atazanavir / cobicistat)
Triumeq
Evotaz (atazanavir / cobicistat)
Triumeq
Summary of Evotaz vs. Triumeq
Summary for Antiretroviral
Prescription only
Evotaz (atazanavir / cobicistat) is a combination medication that's taken as part of an antiretroviral (ARV) regimen to treat HIV (human immunodeficiency virus). It's approved for people with HIV who weigh at least 77 pounds. Evotaz (atazanavir / cobicistat) is a tablet that's taken once a day with food. It must be taken along with other HIV ARV medications. Evotaz (atazanavir / cobicistat) can cause side effects, including rash and jaundice (yellowing of the skin or eyes).
Summary for HIV ARV
Prescription only
Triumeq is a single-tablet regimen used to treat human immunodeficiency virus (HIV) infections. It contains 3 antiretrovirals (ARVs): abacavir, dolutegravir, and lamivudine. Triumeq is available as either a tablet or a dissolvable tablet for oral suspension (Triumeq PD), but the two are not the same. Before starting treatment, your provider will require you to get a genetic test to see if you're at risk for developing a serious allergic reaction to this medication.
Indications of Evotaz vs. Triumeq
Indications for
•Treatment of HIV
Indications for
•Treatment of HIV infection (in people who weigh at least 22 pounds)
Pros and Cons of Evotaz vs. Triumeq
Pros and Const for Antiretroviral
Pros
•Taken once a day
•Combination tablet, so there are fewer pills to take
•Same dose for adults and children who weigh at least 77 pounds