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Compare Evotaz vs. Genvoya

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Evotaz (atazanavir/cobicistat) and Genvoya (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide) are both antiretroviral medications used to treat HIV. They both contain cobicistat, which acts as a "booster" to enhance the effectiveness of other components. However, they differ in their composition and specific roles in HIV treatment. Evotaz combines atazanavir, a protease inhibitor, with cobicistat and must be taken with other HIV medications, as it is not a complete regimen on its own. In contrast, Genvoya is a complete regimen that includes elvitegravir, an integrase strand transfer inhibitor, along with two nucleoside reverse transcriptase inhibitors (NRTIs), emtricitabine and tenofovir alafenamide. Both medications are only available in a branded version. Common side effects of Evotaz include jaundice and rash, whereas Genvoya may cause nausea and diarrhea. Both medications have significant drug interactions, but Genvoya specifically warns against use with certain medications like carbamazepine and lovastatin. Neither medication is recommended during pregnancy.

  • Evotaz (atazanavir / cobicistat)
    Genvoya
  • Evotaz (atazanavir / cobicistat)
    Genvoya

  • Summary of Evotaz vs. Genvoya

    Summary for Antiretroviral
    Prescription only

    Evotaz (atazanavir / cobicistat) is a combination medication that's taken as part of an antiretroviral (ARV) regimen to treat HIV (human immunodeficiency virus). It's approved for people with HIV who weigh at least 77 pounds. Evotaz (atazanavir / cobicistat) is a tablet that's taken once a day with food. It must be taken along with other HIV ARV medications. Evotaz (atazanavir / cobicistat) can cause side effects, including rash and jaundice (yellowing of the skin or eyes).

    Summary for HIV ARV combo
    Prescription only

    Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide) is a combination antiretroviral therapy (ART) that treats human immunodeficiency virus (HIV) infections in adults and children. It's made up of two nucleoside reverse transcriptase inhibitors (NRTIs), emtricitabine and tenofovir alafenamide; an integrase strand transfer inhibitor (INSTI) called elvitegravir; and a "booster" medication known as cobicistat. Genvoya is taken by mouth, typically once daily. Some common side effects of this medication include nausea and diarrhea. It's not available as a generic medication.

  • Indications of Evotaz vs. Genvoya

    Indications for
    •Treatment of HIV
    Indications for
    •Treatment of HIV infection

  • Pros and Cons of Evotaz vs. Genvoya

    Pros and Const for Antiretroviral
    Pros
    •Taken once a day
    •Combination tablet, so there are fewer pills to take
    •Same dose for adults and children who weigh at least 77 pounds
    •Can take if you have a sulfa allergy
    Cons
    •Need to take with food
    •Might cause jaundice (yellowing of skin or eyes)
    •Interacts with a lot of medications, such as certain other HIV medications, statins, and certain blood thinners
    •Must be separated from medications that treat heartburn and indigestion by a certain amount of time
    Pros and Const for HIV ARV combo
    Pros
    •Is a complete regimen for HIV treatment
    •Only taken once a day
    •Taken by mouth
    Cons
    •Needs to be taken with food
    •Can’t take while pregnant
    •Can worsen hepatitis B if you stop taking the medication all of a sudden

  • Common Side Effects of Evotaz vs. Genvoya

    Common Side Effects for
    •Jaundice (yellowing of the skin or eyes; up to 6%)
    •Rash (5%)
    Common Side Effects for
    •Nausea (11%)
    •Diarrhea (7%)
    •Headache (6%)
    •Feeling tired (5%)

  • Warnings of Evotaz vs. Genvoya

    Common Side Effects for
    •Heart rhythm problems
    •Rash and other severe skin reactions
    •Kidney problems
    •Kidney stones or gallstones
    •Liver problems
    •High bilirubin levels
    •Interactions with other medications (including certain HIV ARVs)
    •Overactive immune system
    •High blood sugar
    •Changes in body fat
    •Risk of bleeding in people with hemophilia
    Common Side Effects for
    •Worsening of hepatitis B infection
    •Kidney problems
    •Liver problems and lactic acidosis
    •Overactive immune system
    •Interaction with other medications

  • Prices with our coupons for Evotaz vs. Genvoya

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