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Compare Videx vs. Triumeq

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Didanosine (Videx) and Triumeq (abacavir/dolutegravir/lamivudine) are both antiretroviral (ARV) medications used to treat HIV infections. However, they belong to different subclasses within the ARV class. Didanosine is a nucleoside reverse transcriptase inhibitor (NRTI), while Triumeq is a combination of three medications: abacavir and lamivudine, which are also NRTIs, and dolutegravir, an integrase inhibitor. Didanosine is no longer available in the U.S. due to serious side effects and limited demand, whereas Triumeq is available by prescription and combines three medications into one pill for convenience. Triumeq requires a genetic test before starting treatment to check for a risk of serious allergic reactions, and it is available in tablet form and as a dissolvable tablet for children. Didanosine had serious side effects and drug interactions that limited its use, while Triumeq can cause allergic reactions, liver problems, and interacts with many medications. Triumeq is taken once daily, but its dose cannot be adjusted for people with kidney or liver problems.

  • Didanosine (Videx)
    Triumeq
  • Didanosine (Videx)
    Triumeq

  • Summary of Videx vs. Triumeq

    Summary for HIV ARV

    Didanosine (Videx) was one of the first HIV antiretroviral (ARV) medications approved by the FDA. It has a lot of serious side effects that have limited its use in recent years and is no longer available in the U.S.

    Summary for HIV ARV
    Prescription only

    Triumeq is a single-tablet regimen used to treat human immunodeficiency virus (HIV) infections. It contains 3 antiretrovirals (ARVs): abacavir, dolutegravir, and lamivudine. Triumeq is available as either a tablet or a dissolvable tablet for oral suspension (Triumeq PD), but the two are not the same. Before starting treatment, your provider will require you to get a genetic test to see if you're at risk for developing a serious allergic reaction to this medication.

  • Indications of Videx vs. Triumeq

    Indications for
    Indications for
    •Treatment of HIV infection (in people who weigh at least 22 pounds)

  • Pros and Cons of Videx vs. Triumeq

    Pros and Const for HIV ARV
    Pros
    Cons
    Pros and Const for HIV ARV
    Pros
    •Only taken once a day for complete HIV treatment
    •Combines three medications into one pill for convenience
    •Can be taken with or without food
    •Available for adults and children at or over 22 lbs
    Cons
    •Dose can't be adjusted so it's not recommended for people with kidney or liver problems
    •Not safe to use in severe liver problems
    •Requires a genetic test before starting
    •Interacts with a lot of medications such as St. John’s wort and oxcarbazepine (Trileptal)

  • Common Side Effects of Videx vs. Triumeq

    Common Side Effects for
    Common Side Effects for
    •Higher lipase levels (suggesting irritated pancreas) (up to 11%)
    •Higher blood sugar levels (up to 9%)
    •Higher creatine kinase levels in the blood (suggesting muscle damage) (up to 7%)
    •Higher fat levels in the blood (up to 6%)
    •Higher white blood cell count (up to 4%)
    •Abnormal liver labs (up to 3%)
    •Trouble sleeping (3%)
    •Headache (2%)
    •Feeling tired (2%)

    Please note: The side effects listed above are from clinical trials with Tivicay (dolutegravir) and Epzicom (abacavir / lamivudine), which are all active ingredients in Triumeq and Triumeq PD

  • Warnings of Videx vs. Triumeq

    Common Side Effects for
    Common Side Effects for
    •Serious allergic reaction
    •Worsening of hepatitis B virus (HBV) infection
    •Liver problems
    •Overactive immune system
    •Interaction with other medications

  • Prices with our coupons for Videx vs. Triumeq

    Learn more about Didanosine
    Learn more about Triumeq

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