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Compare Videx vs. Baraclude

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Didanosine (Videx) and entecavir (Baraclude) are both antiviral medications, but they are used to treat different conditions. Didanosine is an antiretroviral (ARV) medication that was used to treat HIV, while entecavir is primarily used for hepatitis B. Both medications belong to the nucleoside reverse transcriptase inhibitor (NRTI) class, but didanosine is no longer available in the U.S. due to serious side effects and limited demand. Entecavir, on the other hand, is still available and is considered a first-choice treatment for hepatitis B. It comes in both tablet and liquid forms, with the tablet having a generic version. Didanosine had significant side effects and drug interactions, which contributed to its discontinuation. Entecavir's common side effects include headache and fatigue, and it requires careful dosing, especially for those with kidney problems. Unlike didanosine, entecavir must be taken on an empty stomach and is not recommended for people with both hepatitis B and untreated HIV.

  • Didanosine (Videx)
    Entecavir (Baraclude)
  • Didanosine (Videx)
    Entecavir (Baraclude)

  • Summary of Videx vs. Baraclude

    Summary for HIV ARV

    Didanosine (Videx) was one of the first HIV antiretroviral (ARV) medications approved by the FDA. It has a lot of serious side effects that have limited its use in recent years and is no longer available in the U.S.

    Summary for Antiviral
    Prescription only

    Entecavir (Baraclude) is a first-choice antiviral medication used for the treatment of hepatitis B. Some side effects of the medication can include headache and fatigue. Entecavir (Baraclude) is available as a tablet and a liquid solution that are typically taken once daily. While both forms of the medication have a brand name, only the tablet has a generic version available as well.

  • Indications of Videx vs. Baraclude

    Indications for
    Indications for
    •Hepatitis B virus (HBV)

  • Pros and Cons of Videx vs. Baraclude

    Pros and Const for HIV ARV
    Pros
    Cons
    Pros and Const for Antiviral
    Pros
    •First-choice medication for hepatitis B
    •Generally mild side effects
    •Not known to have a risk of kidney damage like other hepatitis B medications (e.g., tenofovir (Viread))
    •Can use in children as young as 2 years old
    •Available as a liquid solution for young children and people who have a hard time swallowing tablets
    Cons
    •Not a cure for hepatitis B
    •Must take on an empty stomach (at least 2 hours after a meal and 2 hours before your next meal)
    •Requires dose adjustments for people with kidney problems
    •Not the best option for people who’ve taken lamivudine (Epivir HBV) in the past because of possible viral resistance
    •Not a first-choice option for people with both hepatitis B and HIV

  • Common Side Effects of Videx vs. Baraclude

    Common Side Effects for
    Common Side Effects for
    •Headache
    •Fatigue
    •Dizziness
    •Nausea
    •Higher liver lab results

  • Warnings of Videx vs. Baraclude

    Common Side Effects for
    Common Side Effects for
    •Worsening of hepatitis B after stopping treatment
    •Hepatitis B and HIV co-infection
    •Lactic acidosis and liver problems

  • Prices with our coupons for Videx vs. Baraclude

    Learn more about Didanosine
    Learn more about Entecavir

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