Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Prezista vs. Kaletra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Prezista (darunavir)
    Kaletra (lopinavir / ritonavir)
  • Prezista (darunavir)
    Kaletra (lopinavir / ritonavir)

  • Summary of Prezista vs. Kaletra

    Summary for HIV ARV
    Prescription only

    Prezista (darunavir) is an oral tablet or suspension that's used as part of an antiretroviral (ARV) regimen to treat human immunodeficiency virus (HIV) infections. It's often taken in combination with a "booster," like ritonavir (Norvir), to help Prezista (darunavir) work better against the virus. Rarely, this medication can cause a skin rash within the first month of treatment, but it typically goes away on its own. Lastly, let your provider know if you have a history of sulfa allergy since Prezista (darunavir) contains a "sulfa" component.

    Summary for HIV ARV
    Prescription only

    Kaletra (lopinavir / ritonavir) is a combination medication that's used as part of an antiretroviral (ARV) regimen to treat human immunodeficiency virus (HIV) infections. This medication comes in two different formulations (oral solution and tablets), both of which are taken by mouth. The dosage for Kaletra (lopinavir / ritonavir) depends on your age, the other medications that you're taking (including other medications for HIV), and your other health conditions. Some common side effects include diarrhea and nausea.

  • Indications of Prezista vs. Kaletra

    Indications for
    •Treatment of HIV infection in people aged 3 years and older
    Indications for
    •Treatment of HIV infection (used with other antiretroviral medications)

  • Pros and Cons of Prezista vs. Kaletra

    Pros and Const for HIV ARV
    Pros
    •Taken once a day by mouth
    •Available as an oral suspension, so it's convenient if you have trouble swallowing pills
    •Safe to take during pregnancy
    Cons
    •Requires regular blood work and lab tests
    •Interacts with many medications
    •Must be used carefully in people with sulfa allergies
    Pros and Const for HIV ARV
    Pros
    •Can use in young children aged 2 weeks or older
    •Can take once or twice daily, depending on your medical history
    •Tablets can be taken with or without food
    •Available in a liquid form for people who have difficulty swallowing pills
    Cons
    •Requires regular blood work and lab tests
    •Might need to take up to 4 tablets for one dose
    •Might raise blood sugar, body fat, and cholesterol levels
    •Interacts with a lot of medications (e.g., statins, heart rhythm medications, erectile dysfunction medications)

  • Common Side Effects of Prezista vs. Kaletra

    Common Side Effects for
    •Diarrhea (9-14%)
    •Rash (6-7%)
    •Nausea (4-7%)
    •Headache (3-7%)
    •Stomach pain (6%)
    •Vomiting (2-5%)

    Side effects above were reported in adults taking this medication with ritonavir (Norvir). Side effects might differ in children.

    Common Side Effects for

    Adults:

    •Diarrhea (20%)
    •Respiratory tract infection (8-14%)
    •Nausea (10%)
    •Feeling weak (8%)
    •High cholesterol levels (7%)
    •Vomiting (7%)
    •Belly pain (6%)
    •Muscle, joint, or back pain (6%)
    •Headache or migraine (6%)

    Children:

    •Changes in taste (21%)
    •Vomiting (21%)
    •Diarrhea (12%)

  • Warnings of Prezista vs. Kaletra

    Common Side Effects for
    •Liver problems
    •Severe skin and allergic reactions
    •Changes in body fat
    •Overactive immune system
    •Bleeding
    •Interactions with other medications
    Common Side Effects for
    •Interactions with other medications
    •Pancreas problems
    •Liver problems
    •Heart rhythm problems
    •High blood sugar
    •Overactive immune system
    •Higher cholesterol levels
    •Changes in body fat
    •Risk of bleeding in people with a genetic bleeding problem called hemophilia
    •Potential harm to premature newborns (oral solution only)

  • Prices with our coupons for Prezista vs. Kaletra

    Learn more about Prezista
    Learn more about Kaletra

Compare other HIV Treatment drugs

Prezista vs AptivusPrezista vs CrixivanPrezista vs EvotazPrezista vs GenvoyaPrezista vs InvirasePrezista vs KaletraPrezista vs LexivaPrezista vs PrezcobixPrezista vs StribildPrezista vs TriumeqPrezista vs ViraceptAtripla vs GenvoyaAtripla vs TriumeqEpivir vs GenvoyaEvotaz vs GenvoyaEvotaz vs PrezcobixEvotaz vs StribildEvotaz vs TriumeqGenvoya vs CompleraGenvoya vs DescovyGenvoya vs EdurantGenvoya vs SustivaKaletra vs AptivusPrezcobix vs GenvoyaPrezcobix vs KaletraPrezcobix vs ReyatazPrezcobix vs StribildPrezcobix vs TriumeqTivicay vs GenvoyaZiagen vs Genvoya
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.