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Compare Genvoya vs. Edurant

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Genvoya (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide) and Edurant (rilpivirine) are both medications used to treat HIV, but they have some key differences. Genvoya is a combination of four medications, including two NRTIs, an INSTI, and a booster, and is taken once daily with food. Edurant, on the other hand, is a single NNRTI medication that must be taken with other antiretroviral medications and is also taken once daily with a meal. Both medications are available only as a brand-name medication. Genvoya is not recommended for use during pregnancy, while Edurant can be used during pregnancy. Edurant can be used short-term before starting Cabenuva injections. Both medications have specific side effects and interactions with other medications, so it's important to follow your healthcare provider's instructions closely.

  • Genvoya
    Edurant (rilpivirine)
  • Genvoya
    Edurant (rilpivirine)

  • Summary of Genvoya vs. Edurant

    Summary for HIV ARV combo
    Prescription only

    Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide) is a combination antiretroviral therapy (ART) that treats human immunodeficiency virus (HIV) infections in adults and children. It's made up of two nucleoside reverse transcriptase inhibitors (NRTIs), emtricitabine and tenofovir alafenamide; an integrase strand transfer inhibitor (INSTI) called elvitegravir; and a "booster" medication known as cobicistat. Genvoya is taken by mouth, typically once daily. Some common side effects of this medication include nausea and diarrhea. It's not available as a generic medication.

    Summary for HIV ARV
    Prescription only

    Edurant (rilpivirine) is a once-daily antiretroviral medication that's taken by mouth and is used to treat human immunodeficiency virus (HIV) infection. It's approved for use in adults and children. Edurant (rilpivirine) is taken with other antiretroviral medications when it's used for certain people who've never had HIV treatment before. Edurant (rilpivirine) can also be used for a short period of time before starting Cabenuva (cabotegravir / rilpivirine). Side effects of Edurant (rilpivirine) can include depression, headache, and trouble sleeping.

  • Indications of Genvoya vs. Edurant

    Indications for
    •Treatment of HIV infection
    Indications for
    •Treatment of HIV-1 infection in people 2 years and older, weighing at least 30 pounds, with an HIV viral load of less than 100,000 copies/mL and who haven't taken HIV medications before
    •Short-term treatment of HIV-1 infection in certain people ages 12 years and older, weighing at least 77 pounds, who are planning to start or planning to miss a dose of Cabenuva (cabotegravir / rilpivirine)

  • Pros and Cons of Genvoya vs. Edurant

    Pros and Const for HIV ARV combo
    Pros
    •Is a complete regimen for HIV treatment
    •Only taken once a day
    •Taken by mouth
    Cons
    •Needs to be taken with food
    •Can’t take while pregnant
    •Can worsen hepatitis B if you stop taking the medication all of a sudden
    Pros and Const for HIV ARV
    Pros
    •Taken by mouth once a day, so it's convenient for people with a busy schedule
    •Can use in people with mild-to-moderate kidney and liver problems
    •Safe to use during pregnancy
    Cons
    •Can cause some allergic skin reactions
    •Must take with a meal
    •Only available as a brand-name medication

  • Common Side Effects of Genvoya vs. Edurant

    Common Side Effects for
    •Nausea (11%)
    •Diarrhea (7%)
    •Headache (6%)
    •Feeling tired (5%)
    Common Side Effects for
    •Higher liver function tests (up to 18%)
    •Higher cholesterol levels (up to 17%)
    •Higher creatinine levels (up to 6%)
    •Feeling depressed (5%)
    •Headache (3%)
    •Trouble sleeping (3%)
    •Rash (3%)

  • Warnings of Genvoya vs. Edurant

    Common Side Effects for
    •Worsening of hepatitis B infection
    •Kidney problems
    •Liver problems and lactic acidosis
    •Overactive immune system
    •Interaction with other medications
    Common Side Effects for
    •Severe skin reactions and allergic reactions
    •Liver problems
    •Depression and suicidal thoughts
    •Overactive immune system
    •Interaction with other medications

  • Prices with our coupons for Genvoya vs. Edurant

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