Key takeaways
Abacavir (Ziagen) and dolutegravir (Tivicay) are both antiretroviral (ARV) medications used to treat HIV. They are often used together in combination therapies, but they belong to different medication classes. Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI), while dolutegravir is an integrase inhibitor. Abacavir is available as a generic and can be taken as a tablet or oral solution, whereas dolutegravir is only available as a brand-name medication and comes in tablet form, including a version that can be dissolved in water for those who have trouble swallowing. Abacavir requires a genetic test before starting due to the risk of severe allergic reactions, while dolutegravir can cause liver problems and should not be taken with certain medications like dofetilide. Common side effects of abacavir include headache and nausea, while dolutegravir may cause trouble sleeping and headaches. Both medications can cause serious allergic reactions, so it's important to be aware of the symptoms and seek medical help if needed.
