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Epzicom vs. Combivir

Epzicom (abacavir/lamivudine) and Combivir (lamivudine/zidovudine) are both combination medications used to treat HIV. Both contain lamivudine, but Epzicom pairs it with abacavir, while Combivir pairs it with zidovudine. Epzicom is taken once daily, whereas Combivir needs to be taken twice daily. Epzicom requires a genetic test before starting due to the risk of a severe allergic reaction, while Combivir does not. Combivir can cause serious blood and muscle problems, which are not common with Epzicom. Both medications are available in generic forms, making them more affordable. However, neither is recommended for people with kidney or liver problems since their doses can't be adjusted.