Head-to-head comparisons of medication uses, side effects, warnings, and more.
Tenofovir disoproxil fumarate (Viread)
Intron a (interferon alfa-2b)
Tenofovir disoproxil fumarate (Viread)
Intron a (interferon alfa-2b)
Summary of Viread vs. Intron A
Summary for Antiretroviral (ARV)
Prescription only
Tenofovir disoproxil fumarate (Viread), also known as TDF, is a first-choice medication that's used as part of an antiretroviral (ARV) regimen for treating human immunodeficiency virus (HIV) infections. It's also a preferred medication used for treating hepatitis B virus (HBV). Tenofovir disoproxil fumarate, the active ingredient in Viread, is also found in Truvada, a combination medication commonly used for HIV PrEP. Tenofovir disoproxil fumarate (Viread) is available as both an oral tablet and a powder that's mixed with soft food. Common side effects include rash, diarrhea, and headache.
Summary for Biologic
Intron A (interferon alfa-2b) is an injectable medication that's used to treat various types of cancer and viral infections. Depending on the condition, this medication can be injected into the muscle, under the skin, into a vein, or into an area of skin growth. Intron A (interferon alfa-2b) has been discontinued by the manufacturer and is no longer available in the United States. Your healthcare provider will help guide you to other treatment options.
Indications of Viread vs. Intron A
Indications for
•Treatment of HIV infection - people ages 2 years and older
•Treatment of chronic (long-term) hepatitis B - Brand Viread for people ages 2 years and older; generic for people ages 12 years and older
Indications for
Certain cancers:
•Hairy cell leukemia
•Melanoma
•Follicular lymphoma
•Kaposi's sarcoma in people with AIDs (acquired immunodeficiency syndrome)
Certain viral infections:
•Genital warts
•Chronic (long-term) hepatitis B and C
Pros and Cons of Viread vs. Intron A
Pros and Const for Antiretroviral (ARV)
Pros
•Can treat both HIV and HBV infections
•Only taken once a day
•Available in a powder form that can be mixed with soft foods for people who have difficulty swallowing pills
•Tablet form is available as a lower-cost generic medication
Cons
•Requires regular blood work and lab tests to make sure your liver and kidneys are healthy
•Can worsen hepatitis B if stopped all of a sudden
•More likely to cause bone problems compared to similar medications