Key takeaways
Tenofovir disoproxil fumarate (Viread) and Descovy (emtricitabine/tenofovir alafenamide) are both antiretroviral medications used to treat HIV, but they have some key differences. Viread is also approved to treat hepatitis B, while Descovy is not. Viread can be used in combination with other medications for HIV pre-exposure prophylaxis (PrEP), whereas Descovy is a complete regimen for PrEP but is not effective for females at risk through receptive vaginal sex. Viread is available as a generic, making it a lower-cost option, while Descovy does not have a generic form. Descovy is considered safer for your kidneys and bones compared to Viread. Both medications are taken once daily and require regular blood tests to monitor your health. Common side effects for Viread include rash, diarrhea, and headache, while Descovy commonly causes nausea and diarrhea.
