Key takeaways
Abacavir (Ziagen) and Epzicom (abacavir/lamivudine) are both used to treat HIV, but they have some key differences. Abacavir (Ziagen) is a single medication that belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class and is available in both brand and generic forms. Epzicom, on the other hand, is a combination of two NRTIs, abacavir and lamivudine, and is also available in both brand and generic forms. Epzicom offers the convenience of once-daily dosing with a single tablet, while abacavir (Ziagen) can be taken either once or twice daily. Both medications should be used in combination with other HIV treatments. Both medications also require a genetic test before use due to the risk of a severe allergic reaction. However, Epzicom is not recommended for people with kidney or liver problems because its dose cannot be adjusted. Both medications share similar side effects and risks, including the potential for severe allergic reactions and heart problems. Additionally, Epzicom has a specific warning for people with hepatitis B, as stopping the medication can worsen the condition.
