Key takeaways
Abacavir (Ziagen) and Triumeq (abacavir/dolutegravir/lamivudine) are both used to treat HIV, but they have some key differences. Abacavir (Ziagen) is a single medication that belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class and is available in both generic and brand forms. It should be used in combination with other HIV medications. Triumeq, on the other hand, is a combination of three medications: abacavir, dolutegravir (an integrase inhibitor), and lamivudine (another NRTI). This combination makes Triumeq a complete HIV treatment in one pill, which is taken once daily. Unlike abacavir (Ziagen), Triumeq is not recommended for people with kidney or severe liver problems and has more drug interactions. Both medications require genetic testing for the HLA-B 5701 gene to avoid serious allergic reactions. Triumeq is available in tablet form for adults and children over 55 lbs. Triumeq PD is a dissolvable tablet for children between 13 lbs and 54 lbs.
