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Gemtesa vs. Vesicare

Gemtesa (vibegron) is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa (vibegron) belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.

• Overactive bladder (OAB)
• Overactive bladder in people who are taking medications for benign prostatic hyperplasia (BPH)

• Headache (4%)
• Cold symptoms (3%)
• Diarrhea (2%)
• Nausea (2%)
• Upper respiratory tract infection (2%)

• Angioedema (swelling of face, mouth, throat, or other organ)
• Risk of difficulty emptying the bladder completely

Solifenacin succinate, also known by the brand name Vesicare, is an anticholinergic medication that's used to treating certain bladder problems. The brand-name and generic tablets help treat overactive bladder in adults. A liquid suspension under the brand name Vesicare LS is also available for children with neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem). This medication is taken by mouth once per day. The most common side effects are dry mouth and constipation.

• Overactive bladder in adults - tablets only
• Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only

• Dry mouth (up to 28% in adults, 8% in children)
• Constipation (up to 13% in adults, 3% in children)

• Swelling of the face and possible breathing problems (angioedema)
• Side effects related to the nervous system
• Caution in people with digestive system problems
• Caution in people with glaucoma
• QT prolongation (heart rhythm problem)