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Eucrisa vs. Hydrocortisone

Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

• Mild-to-moderate eczema

• Pain, burning, or stinging where the medication is applied (4%)

• Allergic reactions

Topical hydrocortisone is a steroid medication used to treat different skin conditions, such as eczema. It's available in many different formulations, including cream, ointment, lotion, and solution. Some strengths are found over the counter (e.g., hydrocortisone 1%), while you need a prescription for others (e.g., hydrocortisone 2.5%). In general, most people experience few to no side effects while using topical hydrocortisone as directed. Rarely, topical hydrocortisone might cause topical steroid withdrawal (TSW). Watch out for skin rashes and irritations that get worse after stopping this medication.

Short-term relief of skin irritations (e.g., itching) due to:

• Skin inflammation
• Skin rashes
• Eczema
• Psoriasis
• Insect bites
• Poison ivy or oak
• Skin allergies
• Dry scalp
• Genital or rectal irritation

• Burning
• Itching
• Skin irritation
• Dry skin
• Inflamed hair follicles

• Hormone problems and withdrawal
• High blood sugar
• New or worsened skin infection
• Skin problems