Key takeaways
Ubrelvy (ubrogepant) and Nurtec ODT (rimegepant) are both medications used to treat migraines in adults and belong to the same drug class, calcitonin gene-related peptide (CGRP) receptor blockers. However, they have some differences. Ubrelvy is only approved for treating sudden migraine attacks, while Nurtec ODT is approved for both treating and preventing migraines. Ubrelvy is taken as a regular tablet, with a typical dose of 50 mg to 100 mg, and can be taken up to twice a day. In contrast, Nurtec ODT is a 75 mg orally disintegrating tablet that dissolves on or under your tongue, and is taken once a day as needed for treatment or every other day regularly for prevention. Ubrelvy can cause side effects like nausea, sleepiness, and dry mouth, while Nurtec ODT may cause nausea and stomach pain. Both medications have a lot of drug interactions. Always be sure your pharmacist and prescriber have a complete medication list, including any OTC or herbal supplements you take.
