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Compare Aimovig vs. Ajovy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Aimovig (erenumab) and Ajovy (fremanezumab) are both used to prevent migraines in adults, but they have some differences. Aimovig is a calcitonin gene-related peptide (CGRP) receptor antagonist, while Ajovy is a CGRP receptor blocker. Both work to block the proteins involved with migraine pain. Aimovig is injected once a month, whereas Ajovy offers two dosing options: once a month or once every three months. Both medications are available only as brand-name options and come in prefilled syringes or autoinjectors. Aimovig can cause constipation and high blood pressure, while Ajovy's main side effect is injection-site reactions. Additionally, Aimovig has a specific warning for those with latex allergies, which isn't mentioned for Ajovy. Neither medication is approved for use in children under 18 years old.

drug combination

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  • Aimovig (erenumab)
    Ajovy (fremanezumab)
  • Aimovig (erenumab)
    Ajovy (fremanezumab)

  • Summary of Aimovig vs. Ajovy

    Summary for CGRP receptor antagonist
    Prescription only

    Aimovig (erenumab or erenumab-aooe) is a medication that's used to prevent migraines in adults. It's convenient because it's available as a prefilled autoinjector or syringe, but it's important that you know how to inject the medication properly for it to work. Aimovig (erenumab) is available as a brand-name medication only and is given as an injection under your skin once a month. Possible side effects include pain, swelling, or redness at the injection site and constipation.

    Summary for CGRP receptor blocker
    Prescription only

    Ajovy (fremanezumab or fremanezumab-vfrm) is an injection under the skin that helps prevent migraines in adults. This medication is convenient because it only needs to be used once every month or once every 3 months. The only observed side effects in clinical studies were injection-site reactions (e.g., pain, swelling, redness). Ajovy (fremanezumab) is available as a prefilled autoinjector pen and a prefilled syringe. It's currently only available as a brand-name medication; there's no generic yet.

  • Indications of Aimovig vs. Ajovy

    Indications for
    •Prevention of migraines in adults
    Indications for
    •Prevention of migraines in adults

  • Pros and Cons of Aimovig vs. Ajovy

    Pros and Const for CGRP receptor antagonist
    Pros
    •Taken only once per month
    •Can store at room temperature for up to 7 days, if needed (though typically refrigerated)
    •Available as a prefilled syringe and a prefilled autoinjector
    Cons
    •Must give as an injection under the skin
    •Can't use in children
    •Some autoinjectors and syringes might have parts that are made with dry natural rubber, which can cause allergic reactions in people sensitive to latex.
    Pros and Const for CGRP receptor blocker
    Pros
    •Taken only once per month or once every 3 months
    •Can store at room temperature for up to 7 days, if needed
    •Available as a prefilled syringe and a prefilled autoinjector
    •Manufacturer offers a savings program for certain people
    Cons
    •Might be difficult for some people to use properly
    •Only used for preventing migraines (not for treating a migraine attack)
    •Available as a brand-name medication only
    •Hasn't been studied in children younger than 18 years old

  • Common Side Effects of Aimovig vs. Ajovy

    Common Side Effects for
    •Pain, swelling, or redness at the injection site (5-6%)
    •Constipation (1-3%)
    Common Side Effects for
    •Pain, swelling, or redness at the injection site (43-45%)

  • Warnings of Aimovig vs. Ajovy

    Common Side Effects for
    •Allergic reaction
    •Constipation with serious complications
    •High blood pressure
    Common Side Effects for
    •Allergic reactions

  • Prices with our coupons for Aimovig vs. Ajovy

    Learn more about Aimovig
    Learn more about Ajovy

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