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Compare Xeomin vs. Botox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Xeomin (incobotulinumtoxinA) and Botox (onabotulinumtoxinA) are both injectable treatments that treat several conditions such as eye twitching and muscle spasms. Xeomin is also approved for wrinkles, as is Botox Cosmetic (onabotulinumtoxinA). Botox Cosmetic shows results within 1 to 2 days and lasts up to 4 months, whereas Xeomin takes about 7 days to show effects, lasting 3 to 4 months. One major difference is that Xeomin doesn't contain additives, so it might be a good option if Botox Cosmetic doesn’t work for you. Both require repeat injections and can cause side effects like droopy eyelids and muscle weakness.

drug combination

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  • Xeomin (incobotulinumtoxinA)
    Botox (onabotulinumtoxinA)
  • Xeomin (incobotulinumtoxinA)
    Botox (onabotulinumtoxinA)

  • Summary of Xeomin vs. Botox

    Summary for Neuromuscular blocker
    Prescription only

    Xeomin (incobotulinumtoxinA) is an injectable medication used to treat many movement problems, drooling, and frown lines, but it can have dangerous side effects if it spreads to areas outside of the injection. It's typically administered by a healthcare provider.

    Summary for Neuromuscular blocker
    Prescription only

    Botox (onabotulinumtoxinA) is a prescription injection used for many medical conditions caused by muscle overactivity or nerve problems. It's FDA approved for treating conditions like overactive bladder, excessive armpit sweating, and for preventing migraines. The medication is injected by a trained healthcare professional. Side effects depend on where the injection is given, but they can include urinary tract infections, headache, and neck pain. <br> Botox (onabotulinumtoxinA) is different from Botox Cosmetic, which is used for facial and neck lines.

  • Indications of Xeomin vs. Botox

    Indications for
    •Long-term excessive drooling (sialorrhea) in people 2 years and older
    •Arm spasms in people 2 years and older
    •Uncontrollable neck spasms (cervical dystonia) in adults
    •Uncontrollable eye twitching (blepharospasm) in adults
    •Frown lines in adults
    Indications for
    •Overactive bladder (OAB) - adults
    •Loss of bladder control caused by nerve-bladder problems - adults
    •Nerve-related bladder problem - children 5 years and older
    •Headache prevention for chronic migraine - adults
    •Muscle spasms - adults and children 2 years and older
    •Neck muscle spasms - adults
    •Excessive armpit sweating - adults
    •Eyelid twitching - adults and children 12 years and older
    •Crossed eyes - adults and children 12 years and older

  • Pros and Cons of Xeomin vs. Botox

    Pros and Const for Neuromuscular blocker
    Pros
    •Works well to treat many different movement problems and frown lines
    •Injected directly into the affected muscles
    •Can see improvement in your condition within 7 days
    •Effects typically last 3 to 4 months after each treatment
    Cons
    •Needs to be injected by a healthcare provider
    •Injections can be uncomfortable
    •Requires repeat injections since effects wear off over time
    •Has a risk of swallowing, speaking, or breathing problems
    •Brand only, so might be expensive
    Pros and Const for Neuromuscular blocker
    Pros
    •FDA approved to treat many different conditions
    •Might be a good option when other treatments have failed
    •Injected directly into the area causing trouble
    •Effects last a few months
    Cons
    •Needs to be injected by a healthcare professional
    •Injections can be uncomfortable
    •Has serious risks if the toxin spreads to other parts of your body
    •Might need to get repeat treatments

  • Common Side Effects of Xeomin vs. Botox

    Common Side Effects for

    Excessive drooling:

    •Need for tooth removal (5% in adults)
    •Dry mouth (4% in adults)
    •Diarrhea (4% in adults)
    •High blood pressure (4% in adults)
    •Fall (3% in adults)
    •Bronchitis (3% in adults, 1% in children)
    •Trouble speaking (3% in adults)
    •Back pain (3% in adults)
    •Dry eye (3% in adults)

    Arm spasms:

    •Seizure (3% in adults)
    •Nose and throat infection (2% in adults, 3-6% in children)
    •Bronchitis (2-3% in children)

    Neck spasms:

    •Trouble swallowing (13-18%)
    •Nervous system problems (16-17%)
    •Neck pain (7-15%)
    •Infections (13-14%)
    •Breathing problems (10-13%)
    •Muscle weakness (7-11%)
    •Pain at injection site (4-9%)
    •Muscle or bone pain (4-7%)

    Eye twitching:

    •Drooping eyelid (19%)
    •Dry eye (16%)
    •Dry mouth (16%)
    •Vision changes (e.g., blurred vision, 12%)
    •Injection site reaction (11%)
    •Diarrhea (8%)
    •Headache (7%)
    •Nose and throat infection (5%)
    •Respiratory tract infection (5%)
    •Shortness of breath (5%)

    Frown lines:

    •Headache (5%)
    Common Side Effects for

    Overactive bladder:

    •Urinary tract infection (18%)
    •Painful urination (9%)
    •Trouble emptying the bladder (6%)

    Loss of bladder control:

    •Urinary tract infection (24-26%)
    •Urine left in the bladder (17%)
    •Trouble emptying the bladder (15-17%)
    •Difficulty passing urine (15%)

    Chronic migraine:

    •Neck pain (9%)
    •Headache (5%)

    Muscle spasms:

    •Pain in the arm or leg (up to 9%)
    •Muscle weakness (up to 4%)

    Neck muscle spasm:

    •Trouble swallowing (19%)
    •Upper respiratory infection (12%)
    •Neck pain (11%)
    •Headache (11%)

    Excessive armpit sweating:

    •Injection site pain (3-10%)
    •Bleeding (3-10%)
    •Infection (3-10%)

    Eyelid twitching:

    •Droopy eyelid (21%)
    •Damage to surface of the eye (6%)
    •Dry eye (6%)

    Crossed eyes:

    •Droopy eyelid (1-38%)
    •Eye misalignment (17%)

  • Warnings of Xeomin vs. Botox

    Common Side Effects for
    •Spread of toxin effects
    •Difficulty swallowing or breathing
    •Eye problems due to reduced blinking
    •Worsening of glaucoma
    •Drooping eyelids
    Common Side Effects for
    •Spread of toxin effect
    •Serious allergic reaction
    •Difficulty swallowing or breathing
    •Lung problems in people with breathing conditions
    •Eye problems and bleeding
    •Bronchitis and upper respiratory tract infections
    •Overactive nervous system
    •Urinary tract infections
    •Trouble emptying the bladder
    •Transmission of diseases

  • Prices with our coupons for Xeomin vs. Botox

    Learn more about Xeomin
    Learn more about Botox

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