Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Jeuveau (prabotulinumtoxinA-xvfs) and Botox (onabotulinumtoxinA) are both neuromuscular blockers used to treat wrinkles, specifically frown lines. However, they have different FDA-approved uses. Jeuveau is only approved for cosmetic use to improve moderate-to-severe frown lines in adults, while Botox has a broader range of uses, including treating overactive bladder, chronic migraines, muscle spasms, and excessive sweating. Both medications are given as injections by a healthcare provider, but Botox is available in more dosage forms for different conditions. Jeuveau is typically injected into the forehead, while Botox can be used in various body areas depending on the condition being treated. Common side effects of both medications include headaches and injection site reactions. Both medications carry risks of serious side effects if the toxin spreads/ Botox has additional side effects and warnings related to bladder and eye conditions since it can be administered for other conditions. Neither medication is available in generic form, which may affect cost considerations.
Jeuveau (prabotulinumtoxinA)
Botox (onabotulinumtoxinA)
Jeuveau (prabotulinumtoxinA)
Botox (onabotulinumtoxinA)
Summary of Jeuveau vs. Botox
Summary for Neuromuscular blocker
Prescription only
Jeuveau (prabotulinumtoxinA or prabotulinumtoxinA-xvfs) is a neuromuscular blocker made of botulism toxin. It's injected into certain muscles on the forehead to improve the looks of frown lines in adults. If you need more than one treatment, your HCP can inject Jeuveau (prabotulinumtoxinA) at most once every 3 months. Jeuveau (prabotulinumtoxinA) should only be given by a licensed healthcare professional (HCP) in a healthcare setting. Some common side effects of this medication include headache and pain at the injection site.
Summary for Neuromuscular blocker
Prescription only
Botox (onabotulinumtoxinA) is a prescription injection used for many medical conditions caused by muscle overactivity or nerve problems. It's FDA approved for treating conditions like overactive bladder, excessive armpit sweating, and for preventing migraines. The medication is injected by a trained healthcare professional. Side effects depend on where the injection is given, but they can include urinary tract infections, headache, and neck pain.
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Botox (onabotulinumtoxinA) is different from Botox Cosmetic, which is used for facial and neck lines.
Indications of Jeuveau vs. Botox
Indications for
•Temporary improvement in moderate-to-severe frown lines (glabellar lines) in adults