Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Kybella (deoxycholic acid) and Botox Cosmetic (onabotulinumtoxinA) are both injectable medications used for cosmetic purposes, but they belong to different medication classes and have distinct uses. Kybella is a cytolytic medication used to reduce fat under the chin, commonly known as a "double chin," by destroying fat cells. Botox Cosmetic, on the other hand, is a neuromuscular blocker that temporarily improves the appearance of frown lines, forehead lines, and crow's feet by relaxing facial muscles. While both medications require administration by a healthcare provider, Kybella is injected under the skin, and Botox Cosmetic is injected into the muscles. Kybella treatments can involve up to 50 injections per session, spaced at least a month apart, with a maximum of 6 sessions. Botox Cosmetic treatments are typically given once every 3 months, with a maximum total dose of 400 units in that period. Common side effects of Kybella include swelling, pain, and redness at the injection site, while Botox Cosmetic may cause droopy eyelids and headaches. Both medications are prescription-only and do not have generic versions available.
Kybella (deoxycholic acid)
Botox cosmetic (onabotulinumtoxinA)
Kybella (deoxycholic acid)
Botox cosmetic (onabotulinumtoxinA)
Summary of Kybella vs. Botox Cosmetic
Summary for Cytolytic
Prescription only
Kybella (deoxycholic acid) is an injection used to reduce fat below the chin, helping to minimize the appearance of a "double chin" in adults. It's injected under the skin by a trained healthcare professional, with at least a month between each treatment. You can have up to 6 treatments total, but some people might need fewer. Possible side effects include swelling, pain, and redness at the injection site.
Summary for Neuromuscular blocker
Prescription only
Botox Cosmetic (onabotulinumtoxinA) is a prescription injection used in adults to temporarily improve the look of facial lines. It's FDA approved to treat moderate to severe frown lines between the eyebrows, forehead lines, crow’s feet, and neck lines. The medication is injected directly into the facial muscles by a trained healthcare professional. Side effects can vary depending on the injection site and can include headache and droopy eyelids.
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Botox Cosmetic (onabotulinumtoxinA) is different from medical Botox, which is used for certain health conditions like migraines or muscle spasms.
Indications of Kybella vs. Botox Cosmetic
Indications for
•To improve the appearance of fat below the chin ("double chin")
Indications for
Temporarily improves the appearance of moderate to severe facial lines, including:
•Frown lines
•Crow's feet
•Forehead lines
•Neck lines
Pros and Cons of Kybella vs. Botox Cosmetic
Pros and Const for Cytolytic
Pros
•FDA approved to improve the appearance of a "double chin"
•About 85% of people reported being happy with the results