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Compare Kybella vs. Botox Cosmetic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Kybella (deoxycholic acid) and Botox Cosmetic (onabotulinumtoxinA) are both injectable medications used for cosmetic purposes, but they belong to different medication classes and have distinct uses. Kybella is a cytolytic medication used to reduce fat under the chin, commonly known as a "double chin," by destroying fat cells. Botox Cosmetic, on the other hand, is a neuromuscular blocker that temporarily improves the appearance of frown lines, forehead lines, and crow's feet by relaxing facial muscles. While both medications require administration by a healthcare provider, Kybella is injected under the skin, and Botox Cosmetic is injected into the muscles. Kybella treatments can involve up to 50 injections per session, spaced at least a month apart, with a maximum of 6 sessions. Botox Cosmetic treatments are typically given once every 3 months, with a maximum total dose of 400 units in that period. Common side effects of Kybella include swelling, pain, and redness at the injection site, while Botox Cosmetic may cause droopy eyelids and headaches. Both medications are prescription-only and do not have generic versions available.

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