Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Renova and Retin-A are both topical forms of tretinoin, but they have different FDA-approved uses. Renova is specifically approved to lessen the appearance of fine facial wrinkles, while Retin-A is approved to treat acne in individuals ages 12 and older. Both medications are applied once daily, typically in the evening, and can cause similar side effects , such as skin irritation, redness, and peeling. Both medications can make your skin more sensitive to sunlight, and Retin-A may initially worsen acne before improvement is seen. Neither medication is recommended for use during pregnancy due to potential risks to the unborn baby.
Renova (tretinoin)
Retin-a (tretinoin)
Renova (tretinoin)
Retin-a (tretinoin)
Summary of Renova vs. Tretinoin
Summary for Retinoic acid derivative
Prescription only
Renova is a topical retinoid that contains tretinoin 0.02% cream. Renova (tretinoin) can ease fine facial wrinkles, in addition to the regular use of sunscreen and sun-protective clothing. But it won't help get rid of deep wrinkles or hyperpigmentation from years of sun damage. Renova (tretinoin) is applied to the face once daily in the evening. This medication commonly causes skin irritation and peeling as side effects. Renova is a prescription medication that's brand name only and not available as a generic.
Summary for Retinoid
Prescription only
Retin-A (tretinoin) is a retinoid medication that's used to treat acne in adults and children 12 years and older. It's available as a cream or a gel that's applied onto the skin once a day. Side effects include skin irritation, redness, and peeling. Your acne might get worse at the beginning of treatment, but it should get better as you continue using the medication. You must have a prescription for Retin-A (tretinoin) from your primary care provider or dermatologist; this medication isn't available over the counter.