Key takeaways
Renova and Retin-A are both topical forms of tretinoin, but they have different FDA-approved uses. Renova is specifically approved to lessen the appearance of fine facial wrinkles, while Retin-A is approved to treat acne in individuals ages 12 and older. Both medications are applied once daily, typically in the evening, and can cause similar side effects , such as skin irritation, redness, and peeling. Both medications can make your skin more sensitive to sunlight, and Retin-A may initially worsen acne before improvement is seen. Neither medication is recommended for use during pregnancy due to potential risks to the unborn baby.
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