Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Botox Cosmetic (onabotulinumtoxinA) and Jeuveau (prabotulinumtoxinA-xvfs) are both neuromuscular blockers used to temporarily improve the appearance of frown lines in adults but there are some differences between them. They work by blocking a chemical called acetylcholine, which relaxes the muscles and smooths out wrinkles. However, Botox Cosmetic is also FDA-approved to treat forehead lines and crow's feet, while Jeuveau is only approved for frown lines. Botox Cosmetic can be used for multiple facial areas at once, but Jeuveau is specifically injected into the forehead. The dosing for Botox Cosmetic can vary, with 20 to 40 units per treatment session, whereas Jeuveau typically involves 20 units per treatment session. Both medications are only available as injections administered by a healthcare provider. Common side effects for both medications include headache, pain at the injection site and droopy eyelids. Neither medication is available in a generic form, and both carry risks of serious side effects if the toxin spreads beyond the injection site.
Botox cosmetic (onabotulinumtoxinA)
Jeuveau (prabotulinumtoxinA)
Botox cosmetic (onabotulinumtoxinA)
Jeuveau (prabotulinumtoxinA)
Summary of Botox Cosmetic vs. Jeuveau
Summary for Neuromuscular blocker
Prescription only
Botox Cosmetic (onabotulinumtoxinA) is a prescription injection used in adults to temporarily improve the look of facial lines. It's FDA approved to treat moderate to severe frown lines between the eyebrows, forehead lines, crow’s feet, and neck lines. The medication is injected directly into the facial muscles by a trained healthcare professional. Side effects can vary depending on the injection site and can include headache and droopy eyelids.
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Botox Cosmetic (onabotulinumtoxinA) is different from medical Botox, which is used for certain health conditions like migraines or muscle spasms.
Summary for Neuromuscular blocker
Prescription only
Jeuveau (prabotulinumtoxinA or prabotulinumtoxinA-xvfs) is a neuromuscular blocker made of botulism toxin. It's injected into certain muscles on the forehead to improve the looks of frown lines in adults. If you need more than one treatment, your HCP can inject Jeuveau (prabotulinumtoxinA) at most once every 3 months. Jeuveau (prabotulinumtoxinA) should only be given by a licensed healthcare professional (HCP) in a healthcare setting. Some common side effects of this medication include headache and pain at the injection site.
Indications of Botox Cosmetic vs. Jeuveau
Indications for
Temporarily improves the appearance of moderate to severe facial lines, including:
•Frown lines
•Crow's feet
•Forehead lines
•Neck lines
Indications for
•Temporary improvement in moderate-to-severe frown lines (glabellar lines) in adults
Pros and Cons of Botox Cosmetic vs. Jeuveau
Pros and Const for Neuromuscular blocker
Pros
•Can treat many facial and neck lines at the same time