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Compare Botox Cosmetic vs. Jeuveau

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Botox Cosmetic (onabotulinumtoxinA) and Jeuveau (prabotulinumtoxinA-xvfs) are both neuromuscular blockers used to temporarily improve the appearance of frown lines in adults but there are some differences between them. They work by blocking a chemical called acetylcholine, which relaxes the muscles and smooths out wrinkles. However, Botox Cosmetic is also FDA-approved to treat forehead lines and crow's feet, while Jeuveau is only approved for frown lines. Botox Cosmetic can be used for multiple facial areas at once, but Jeuveau is specifically injected into the forehead. The dosing for Botox Cosmetic can vary, with 20 to 40 units per treatment session, whereas Jeuveau typically involves 20 units per treatment session. Both medications are only available as injections administered by a healthcare provider. Common side effects for both medications include headache, pain at the injection site and droopy eyelids. Neither medication is available in a generic form, and both carry risks of serious side effects if the toxin spreads beyond the injection site.

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