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Cleocin T vs. MetroGel-Vaginal

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cleocin (clindamycin) and Metrogel (metronidazole) are both antibiotics, but they are used for different conditions and come in different forms. Cleocin (clindamycin) is a lincosamide antibiotic used as a vaginal suppository to treat bacterial vaginosis, while Metrogel (metronidazole) is a nitroimidazole antibiotic used topically to treat rosacea, a type of adult acne. Cleocin is only available as a brand-name medication, making it potentially more expensive, whereas Metrogel is available in generic forms, which can be more affordable. Cleocin is typically used once daily for 3 days, whereas Metrogel needs to be applied daily and may take 3-4 weeks to show significant improvement. Cleocin can cause local side effects like vaginal irritation and yeast infections, while Metrogel can cause skin dryness, stinging, and irritation. Additionally, Cleocin should not be used with tampons or during vaginal sex, as it can weaken condoms and diaphragms, whereas Metrogel allows for the use of makeup and moisturizers.

Clindamycin

(Cleocin-T)

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Metrogel

(metronidazole)

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Summary for Cleocin T

Prescription only

Clindamycin (Cleocin-T) is a topical antibiotic that is used to treat mild to moderate acne. When combined with other acne medications like benzoyl peroxide or retinoids like Retin-A, it can work quite well to treat acne. It's also available in many different formulations like lotion, gel, and solution.

Indications for Cleocin T

  • Acne

Pros and Cons for Cleocin T

Pros

  • Available in generic form
  • Comes in different formulations (gel, solution, lotion, foam, swabs) to fit your lifestyle and perference
  • Works well for the kind of acne that causes large, red, and swollen pimples
  • Usually the first choice acne treatment for mild to moderate acne
  • There are prescription medications available that contain clindamycin combined with other popular acne medications like benzoyl peroxide or retinoid.

Cons

  • You will most likely have to use another acne medication along with clindamycin (Cleocin-T) since it doesn't work as well by itself.
  • It's only preferred for mild to moderate acne. If you have severe acne, your healthcare provider will most likely prescribe an oral medication.
  • If you only have comedonal acne (small skin-colored bumps on the skin) without any red, swollen pimples, your healthcare provider may give you a different medication.
  • Topical clindamycin (Cleocin-T) won't cure your acne, but it will help keep your acne under control.
  • You may need to use this medication for many weeks until you see your acne get better.

Common Side Effects for Cleocin T

  • Skin irritation
  • Dryness
  • Redness
  • Peeling
  • Burning
  • Oily skin
  • Skin that's sensitive to the sun

Warnings for Cleocin T

  • SKIN IRRITATION
  • SEVERE DIARRHEA AND STOMACH CRAMPS
  • SUN SENSITIVITY

Summary for MetroGel-Vaginal

Prescription only

Metrogel (metronidazole) is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.

Indications for MetroGel-Vaginal

  • Adult acne

Pros and Cons for MetroGel-Vaginal

Pros

  • Works well to lower the swelling due to adult acne.
  • It has fewer side effects than oral tablets.
  • It is available as a generic product.
  • There are different strengths of Metrogel (metronidazole) available.
  • Available as a gel, lotion and cream.
  • Can still wear make-up under Metrogel (metronidazole).
  • Can be used in elderly people.

Cons

  • Can cause stinging, dryness, or irritation when applied.
  • It takes about 3-4 weeks to see significant improvement while using this medication.
  • Has to be used daily to see benefits from this medication.
  • Safety has not be studied in children.

Common Side Effects for MetroGel-Vaginal

  • Nasopharyngitis - a common cold that affects the nose and throat (3%)
  • Upper respiratory tract infection - a cold that affects the nose, throat, and lungs (3%)
  • Headache (2%)

Source: DailyMed

Warnings for MetroGel-Vaginal

  • EYE IRRITATION
  • WEAKNESS AND TINGLING SENSATION IN THE HANDS AND FEET
  • SKIN RASH

Prices with our coupons for Cleocin T vs. MetroGel-Vaginal

Price Card Drug Icon
Clindamycin21 capsules / 300mg
$14.57-
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Metronidazole1 tube / 45g of 0.75%
$26.26$319.49
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