Key takeaways
Cefuroxime (Ceftin) and cephalexin (Keflex) are both cephalosporin antibiotics used to treat bacterial infections, such as ear infections, sinus infections, and urinary tract infections (UTIs). However, they have some differences. Cefuroxime, previously known by the brand name Ceftin, is available as tablets and injections, while cephalexin, once branded as Keflex, is available as capsules, tablets, and liquid suspensions. Cefuroxime is typically taken 2 times a day, whereas cephalexin can be taken 2 to 4 times a day. Cefuroxime is also used for conditions like gonorrhea and Lyme disease, which are not listed for cephalexin. Both medications can cause side effects like diarrhea and nausea, but cephalexin may also cause dizziness and fatigue. You should avoid heartburn medications with cefuroxime, while cephalexin can interact with metformin and probenecid. Both medications are available as lower-cost generics, but only cephalexin offers a liquid form for those who have trouble swallowing pills.
