Key takeaways
Cefdinir (Omnicef) and Augmentin (amoxicillin/clavulanate) are both antibiotics used to treat bacterial infections, such as sinus and ear infections. However, they belong to different medication classes. Cefdinir is a cephalosporin antibiotic, while Augmentin combines a penicillin antibiotic with a beta-lactamase inhibitor. Cefdinir is available as capsules and oral suspension, typically taken once or twice daily, and is often used off-label for urinary tract infections (UTIs) in children. Augmentin comes in tablets, chewable tablets, and suspension forms, usually taken two to three times daily, and is FDA-approved for UTIs. Generic versions of both medications are available, but Augmentin is generally less expensive. Common side effects for both include diarrhea, nausea, and serious skin reactions, but Augmentin can also cause liver issues. Both medications can interact with warfarin, while cefdinir may interact with antacids and iron supplements.
