Key takeaways
Cephalexin (Keflex) and ceftibuten (Cedax) are both cephalosporin antibiotics used to treat bacterial infections. They share similarities in treating infections of the ears, throat, and respiratory tract. However, cephalexin is also used for skin, bone, urinary tract, and reproductive system infections, while ceftibuten is specifically used for bronchitis, otitis media, and strep throat. Cephalexin is available as a generic medication in capsules, tablets, and liquid forms, whereas ceftibuten, previously sold under the brand name Cedax, is no longer available in the U.S. Cephalexin is typically taken 2 to 4 times a day, while ceftibuten was taken once daily. Common side effects of cephalexin include nausea, vomiting, and diarrhea, and it may interact with medications like metformin and probenecid. Ceftibuten's discontinuation was not due to safety or effectiveness issues, but its availability is limited.
