Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Gatifloxacin (Zymaxid) and Clarithromycin (Biaxin) are both antibiotics, but they are used differently and belong to different classes. Gatifloxacin is a fluoroquinolone antibiotic used as eye drops to treat bacterial conjunctivitis (pink eye) in people aged 1 year and older. It works by blocking proteins bacteria need to reproduce and repair themselves. Clarithromycin, on the other hand, is a macrolide antibiotic taken orally to treat a variety of infections, including lung, sinus, strep throat, and skin infections. It stops bacteria from making certain proteins, preventing them from growing and surviving. Gatifloxacin is only available as eye drops, while Clarithromycin comes in immediate-release tablets, extended-release tablets, and liquid forms. Gatifloxacin is used multiple times a day for about a week, whereas Clarithromycin is typically taken once or twice a day for 7 to 14 days, depending on the infection. Common side effects of Gatifloxacin include eye irritation and changes in taste, while Clarithromycin can cause stomach pain, diarrhea, nausea, vomiting, and changes in taste. Additionally, Clarithromycin has many drug interactions and is not recommended for people with certain heart or liver conditions.
Gatifloxacin (Zymaxid)
Clarithromycin
Gatifloxacin (Zymaxid)
Clarithromycin
Summary of Zymaxid vs. Biaxin
Summary for Fluoroquinolone antibiotic
Prescription only
Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic eye drop. It works well to treat pink eye caused by certain types of bacteria, but it doesn't treat pink eye caused by viruses. Gatifloxacin (Zymaxid) is approved for people ages 1 year and older. It's placed in the eye multiple times a day. Typically, treatment lasts about a week. Some of the more common side effects of gatifloxacin (Zymaxid) include eye irritation and changes in taste in your mouth.
Summary for Macrolide antibiotic
Prescription only
Clarithromycin (previously known by its brand name Biaxin) is an antibiotic that's used to treat a variety of bacterial infections in adults and children. It's available as a generic immediate-release tablet and solution taken twice per day and an extended-release tablet taken once per day. Side effects include a metallic or sour taste, nausea, vomiting, and diarrhea.