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Zymaxid vs. Flagyl

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gatifloxacin (Zymaxid) and Metronidazole (Flagyl) are both antibiotics, but they are used for different types of infections and administered in different ways. Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic used as eye drops to treat bacterial conjunctivitis (pink eye) in people aged 1 year and older. In contrast, Metronidazole (Flagyl) is a nitroimidazole antibiotic taken orally to treat various bacterial and parasitic infections, including trichomoniasis and bacterial vaginosis. Metronidazole is also availible as an injection. Gatifloxacin (Zymaxid) is applied multiple times a day directly to the eye, while Metronidazole (Flagyl) is typically taken by mouth three times a day. You should avoid alcohol while taking Metronidazole (Flagyl) and for three days after stopping it, as it can cause a serious reaction. Gatifloxacin (Zymaxid) is available as a lower-cost generic, and so is Metronidazole (Flagyl). Common side effects of Gatifloxacin (Zymaxid) include eye irritation and changes in taste, whereas Metronidazole (Flagyl) can cause diarrhea, nausea, and a metallic taste in the mouth.

Gatifloxacin

(Zymaxid)

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Metronidazole

(Flagyl)

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Summary for Zymaxid

Prescription only

Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic eye drop. It works well to treat pink eye caused by certain types of bacteria, but it doesn't treat pink eye caused by viruses. Gatifloxacin (Zymaxid) is approved for people ages 1 year and older. It's placed in the eye multiple times a day. Typically, treatment lasts about a week. Some of the more common side effects of gatifloxacin (Zymaxid) include eye irritation and changes in taste in your mouth.

Indications for Zymaxid

Pros and Cons for Zymaxid

Pros

  • Causes fewer serious side effects than oral antibiotics
  • Can be given to children age 1 year or older
  • Available as a lower-cost, generic form

Cons

  • Has to be used multiple times a day
  • Can cause temporary eye irritation after applying
  • Won't be able to treat pink eye caused by virus(es)

Common Side Effects for Zymaxid

  • Worsening of eye infection
  • Eye irritation
  • Eye pain
  • Changes the taste in your mouth

Warnings for Zymaxid

  • Allergic reactions
  • New infection

Summary for Flagyl

Prescription only

Metronidazole (Flagyl) is an oral antibiotic for adults and children. It's used to treat certain bacterial and parasitic infections, including bacterial vaginosis (a type of vaginal bacteria infection) and trichomoniasis (a sexually transmitted infection, or STI). Metronidazole (Flagyl) is taken by mouth, typically 3 times a day. Some common side effects of this medication include diarrhea, nausea, and vomiting. Avoid drinking alcohol while taking and for 3 days after stopping metronidazole (Flagyl) because this combination can cause a serious reaction. Metronidazole (Flagyl) is available as a lower-cost generic.

Indications for Flagyl

Treatment of certain bacterial and parasitic infections, including:

Pros and Cons for Flagyl

Pros

  • Taken by mouth
  • Available as a lower-cost generic medication
  • Can be used to treat different types of bacterial infection
  • Immediate-release formulations can be taken with or without food

Cons

Common Side Effects for Flagyl

Please note: These are common side effects reported by people who took extended-release metronidazole (Flagyl)

  • Headache (18%)
  • Inflammation of the vagina (15%)
  • Nausea (10%)
  • Metallic taste (9%)
  • Flu-like symptoms (6%)

Warnings for Flagyl

  • Possible risk of cancer
  • Serious allergic reactions
  • Brain and nerve problems
  • Liver and kidney problems
  • Risk of fungal infection
  • Risk of drug resistance
  • Lower white blood cell counts
  • Interaction with other medications

Prices with our coupons for Zymaxid vs. Flagyl

Price Card Drug Icon
Gatifloxacin1 eye dropper / 2.5ml of 0.5%
$35.54$124.99
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Price Card Drug Icon
Metronidazole14 tablets / 500mg
$10.73$14.75
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