Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic eye drop. It works well to treat pink eye caused by certain types of bacteria, but it doesn't treat pink eye caused by viruses. Gatifloxacin (Zymaxid) is approved for people ages 1 year and older. It's placed in the eye multiple times a day. Typically, treatment lasts about a week. Some of the more common side effects of gatifloxacin (Zymaxid) include eye irritation and changes in taste in your mouth.
Bacterial conjunctivitis (pink eye)
Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic. It kills bacteria by blocking the proteins they need to reproduce and repair themselves.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Bloody eye
decrease in vision
swelling of the membrane covering the white part of the eye
Rare
Blistering, peeling, or loosening of the skin
chills
joint or muscle pain
red skin lesions, often with a purple center
red, irritated eyes
sores, ulcers, or white spots in the mouth or on the lips
unusual tiredness or weakness
Incidence not known
Difficulty with swallowing
dizziness
fast heartbeat
hives or welts, or skin rash
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the skin
tightness in the chest
trouble breathing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Blurred vision
discharge from the eyes
itching eyes
stringy mucus secretions
swelling of the eye, eyelid, or inner lining of the eyelid
watering eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Causes fewer serious side effects than oral antibiotics
Can be given to children age 1 year or older
Available as a lower-cost, generic form
Has to be used multiple times a day
Can cause temporary eye irritation after applying
Won't be able to treat pink eye caused by virus(es)
Be sure to use gatifloxacin (Zymaxid) for the full amount of time your healthcare provider instructed, even if you start to feel better. Stopping gatifloxacin (Zymaxid) too soon can cause your infection to come back and be harder to treat.
Wash your hands before and after putting gatifloxacin (Zymaxid) drops in your eyes. Don't touch the dropper tip with your eye, hands, or any other surface. This will help avoid spreading germs or bacteria to the solution and your eye.
After placing a drop in your eye, close your eye and press one finger to the inner corner of your eye by the nose for 1 minute. This helps make sure your eye absorbs the drop. Wash your hands with soap and water afterwards.
If you are using gatifloxacin (Zymaxid) at the same time as other eye medications, wait 5 minutes between each drop to give your eyes time to absorb each medication. If you are using an eye ointment at the same time as this medication, use gatifloxacin (Zymaxid) first, wait 5 minutes, and then apply your eye ointment.
Store your gatifloxacin (Zymaxid) bottle at room temperature. Don't put it in the refrigerator or freezer.
Don't wear contacts while using gatifloxacin (Zymaxid). It's usually best not to wear contacts while you have an eye infection, since this can affect how quickly your symptoms improve. Be sure to throw away the contacts you were wearing before you started using gatifloxacin (Zymaxid), as they most likely have bacteria on them. Wear new contacts once your infection is cleared up.
Gatifloxacin (Zymaxid) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Severe allergic reactions to gatifloxacin (Zymaxid) are rare, but can include life-threatening problems, like anaphylaxis (closing of the throat) and Stevens-Johnson Syndrome (severe skin rash and peeling). Let your provider know if you have an allergy to other fluoroquinolone antibiotics, like ciprofloxacin (Cipro), because you might be allergic to gatifloxacin (Zymaxid) as well. If you notice hives, a rash, swelling of the lips or tongue, or difficulty breathing after using gatifloxacin (Zymaxid), call your healthcare provider right away.
Risk factors: Using gatifloxacin (Zymaxid) for too long
Don't use gatifloxacin (Zymaxid) longer than prescribed. Doing so can lead to other types of difficult-to-treat (don't respond to) gatifloxacin (Zymaxid) eye infections. Let your provider know if you notice symptoms of a new eye infection or if the original symptoms don't get better after using gatifloxacin (Zymaxid).
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
2.5ml of 0.5% | 1 eye dropper | $35.44 | $35.44 |
Your optometrist or ophthalmologist will give you specific instructions on how often you should use gatifloxacin (Zymaxid). In general:
Day 1: Place 1 drop in the affected eye(s) every 2 hours, up to 8 times a day.
Days 2 to 7: Place 1 drop in the affected eye(s) 2 to 4 times daily.
You only have to use gatifloxacin (Zymaxid) while you are awake.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Allergy to other fluoroquinolone antibiotics
Bacterial conjunctivitis (pink eye)
Bacterial conjunctivitis (pink eye) - 0.5% strength
Corneal ulcer - 1.5% strength
By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.
Gudgel, D. T., et al. (2023). How to put in eye drops. American Academy of Ophthalmology.
Sandoz Inc. (2021). Gatifloxacin solution/ drops [package insert]. DailyMed.
U.S Food and Drug Administration and Department of Health and Human Services. (2008). Determination that Tequin (gatifloxacin) was withdrawn from sale for reasons of safety or effectiveness. Federal Register.
Willmann, D., et al. (2023). Hordeolum (stye). StatPearls.
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.