Key takeaways
Levofloxacin and Metronidazole (Flagyl) are both antibiotics, but they belong to different classes and treat different types of infections. Levofloxacin is a fluoroquinolone antibiotic used for serious bacterial infections like pneumonia, UTIs, and skin infections. It is typically taken once daily and is available in generic form. However, it has serious side effects, including tendon rupture and nerve damage, and is usually prescribed when safer options aren't available. On the other hand, Metronidazole is a nitroimidazole antibiotic used to treat bacterial and parasitic infections, such as bacterial vaginosis and trichomoniasis. It is taken multiple times a day and also comes in a generic form. Metronidazole has a serious interaction with alcohol and can cause a metallic taste in the mouth. Both medications can cause nausea and headaches.
