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Compare Ethambutol vs. Isoniazid

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ethambutol (Myambutol) and isoniazid (Nydrazid) are both antibiotics used to treat tuberculosis (TB), but they have some key differences. Both medications must be taken with other anti-TB antibiotics for treatment of TB infection. Isoniazid can be taken alone for TB prevention. Ethambutol is only available in tablet form, while isoniazid is available in tablet, liquid and injection forms. Ethambutol can cause vision problems, including optic neuritis, which may lead to blindness if not monitored, whereas isoniazid is more likely to cause serious liver injury and nerve problems. Isoniazid requires you to avoid certain foods like cheese and red wine due to potential interactions, while ethambutol does not have such dietary restrictions. Both medications are affordable in their generic forms and require regular monitoring, but isoniazid may also necessitate taking vitamin B6 supplements to prevent nerve issues.

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