Key takeaways
Ethambutol (Myambutol) and pyrazinamide are both antitubercular agents used to treat active tuberculosis (TB). They are taken with other TB antibiotics like isoniazid and rifampin. Ethambutol (Myambutol) is available as a generic and is taken once daily, with the dose based on body weight. It can cause vision problems, so regular eye exams are necessary. Pyrazinamide is also available as a generic tablet and can be taken once daily or a few times per week. It can cause joint pain and increase uric acid levels, which might lead to gout. Both medications can affect the liver, so liver function needs to be monitored. Ethambutol (Myambutol) is not recommended for children under 13, while pyrazinamide is safe for children. Ethambutol (Myambutol) is also used off-label for some Mycobacteria infections, unlike pyrazinamide.
