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Compare Pyrazinamide vs. Cipro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Pyrazinamide and Ciprofloxacin (Cipro) are both antibiotics, but they treat different types of infections and belong to different drug classes. Pyrazinamide is an antitubercular agent used specifically to treat active tuberculosis (TB) and is taken with other TB medications like isoniazid and rifampin. Ciprofloxacin (Cipro), on the other hand, is a fluoroquinolone antibiotic that treats a variety of bacterial infections, including sinus infections, urinary tract infections (UTIs), and anthrax exposure. Pyrazinamide is typically taken once daily or a few times per week, while Ciprofloxacin (Cipro) is usually taken twice daily. Pyrazinamide can cause side effects like joint pain and liver issues, whereas Ciprofloxacin (Cipro) has more severe potential side effects, such as tendon rupture and nerve damage. Additionally, Ciprofloxacin (Cipro) interacts with many medications and can make your skin more sensitive to the sun, while Pyrazinamide can raise uric acid levels, potentially leading to gout. Both medications are available in generic forms.

  • Pyrazinamide
    Ciprofloxacin (Cipro)
  • Pyrazinamide
    Ciprofloxacin (Cipro)

  • Summary of Pyrazinamide vs. Cipro

    Summary for Antitubercular agent
    Prescription only

    Pyrazinamide is an antibiotic that treats active tuberculosis (TB). It's taken together with other anti-TB medications, such as isoniazid and rifampin. Pyrazinamide can cause side effects like joint or muscle ache, nausea, and vomiting. This medication can also affect the liver and raise your risk for gout. Pyrazinamide is available as a lower-cost generic tablet.

    Summary for Fluoroquinolone antibiotic
    Prescription only

    Ciprofloxacin (Cipro) is a fluoroquinolone antibiotic. It can treat many types of bacterial infections, including sinus infections and urinary tract infections (UTIs). But because ciprofloxacin (Cipro) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when there aren't any safer options. Ciprofloxacin (Cipro) is taken by mouth, typically twice daily. It's available as a pill and oral solution. Some of the more common side effects of this medication include nausea and diarrhea.

  • Indications of Pyrazinamide vs. Cipro

    Indications for
    •Treatment of active tuberculosis (TB)
    Indications for

    Adults only

    •Skin infections
    •Bone and joint infections
    •Sinus infections
    •Lower respiratory tract infections
    •Stomach infections
    •Infectious diarrhea
    •Typhoid fever
    •Gonorrhea in the genitals
    •Long-term prostate infections

    Adults and children

    •Urinary tract infections (UTIs)
    •Anthrax exposure through inhalation
    •Plague

  • Pros and Cons of Pyrazinamide vs. Cipro

    Pros and Const for Antitubercular agent
    Pros
    •One of the first-choice medications used to treat active TB
    •Usually taken for 2 months
    •Can take once per day or a few times per week, depending on your dosing schedule
    •Safe for children to take
    Cons
    •Must take with other anti-TB antibiotics
    •Not a good option for people with severe liver problems
    •Can worsen gout and shouldn't be used in people with recent gout flares
    •Only available in tablet form
    Pros and Const for Fluoroquinolone antibiotic
    Pros
    •Can take with or without food
    •Available as tablets, oral liquid, and injection
    •Possible option for people with penicillin allergy
    Cons
    •Taken twice daily
    •Has many potentially serious side effects and risks (e.g., nerve issues, irregular heartbeat)
    •Interacts with many medications, including metformin and warfarin (Coumadin)

  • Common Side Effects of Pyrazinamide vs. Cipro

    Common Side Effects for
    •Mild joint or muscle ache
    •Nausea
    •Vomiting
    •Loss of appetite
    Common Side Effects for
    •Nausea
    •Diarrhea
    •Vomiting
    •Rash
    •Abnormal liver blood test results

  • Warnings of Pyrazinamide vs. Cipro

    Common Side Effects for
    •Liver injury
    •Gout
    •Caution in people with diabetes
    Common Side Effects for
    •Tendon inflammation and rupture
    •Effects on the brain, nerves, and mental health
    •Worsening of myasthenia gravis
    •Severe allergic and skin reactions
    •Liver damage
    •Severe damage to a major blood vessel
    •Infectious diarrhea
    •Life-threatening abnormal heart rhythm (QT prolongation)
    •Muscle, bone, or joint problems in children
    •Sun and light sensitivity
    •Kidney problems

  • Prices with our coupons for Pyrazinamide vs. Cipro

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    Learn more about Ciprofloxacin

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