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Compare Pyrazinamide vs. Avelox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Pyrazinamide and moxifloxacin (Avelox) are both antibiotics, but they treat different types of infections and belong to different drug classes. Pyrazinamide is an antitubercular agent used to treat active tuberculosis (TB) and is taken with other TB medications like isoniazid and rifampin. Moxifloxacin (Avelox), a fluoroquinolone antibiotic, treats various bacterial infections, including lung, skin, and sinus infections, but is usually reserved for more serious infections due to its potential for severe side effects like tendon rupture and nerve damage. Pyrazinamide is typically taken once daily or a few times per week, while moxifloxacin (Avelox) is taken once daily. Pyrazinamide can cause liver problems and gout, whereas moxifloxacin (Avelox) can lead to tendon issues, heart rhythm problems, and severe allergic reactions. Both medications are available in generic forms, but moxifloxacin (Avelox) is not recommended for children and has many drug interactions.

  • Pyrazinamide
    Moxifloxacin (Avelox)
  • Pyrazinamide
    Moxifloxacin (Avelox)

  • Summary of Pyrazinamide vs. Avelox

    Summary for Antitubercular agent
    Prescription only

    Pyrazinamide is an antibiotic that treats active tuberculosis (TB). It's taken together with other anti-TB medications, such as isoniazid and rifampin. Pyrazinamide can cause side effects like joint or muscle ache, nausea, and vomiting. This medication can also affect the liver and raise your risk for gout. Pyrazinamide is available as a lower-cost generic tablet.

    Summary for Fluoroquinolone antibiotic
    Prescription only

    Moxifloxacin (Avelox) is a fluoroquinolone antibiotic. It can treat different types of infections, including certain skin infections and lung infections, in adults. But because moxifloxacin (Avelox) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when safer options aren't available. Moxifloxacin (Avelox) is taken by mouth, typically once daily. Some of the more common side effects of this medication include nausea, diarrhea, and headache. Moxifloxacin is generic only, brand-name Avelox is no longer available.

  • Indications of Pyrazinamide vs. Avelox

    Indications for
    •Treatment of active tuberculosis (TB)
    Indications for

    Treatment of certain bacterial infections, including:

    •Lung infections (e.g., community acquired pneumonia, chronic bronchitis flare-ups)
    •Skin infections
    •Gut infections
    •Plague
    •Sinus infections

  • Pros and Cons of Pyrazinamide vs. Avelox

    Pros and Const for Antitubercular agent
    Pros
    •One of the first-choice medications used to treat active TB
    •Usually taken for 2 months
    •Can take once per day or a few times per week, depending on your dosing schedule
    •Safe for children to take
    Cons
    •Must take with other anti-TB antibiotics
    •Not a good option for people with severe liver problems
    •Can worsen gout and shouldn't be used in people with recent gout flares
    •Only available in tablet form
    Pros and Const for Fluoroquinolone antibiotic
    Pros
    •Can take with or without food
    •Only taken once a day
    •Treats many types of infections
    •Might be an option for people who have penicillin allergy
    Cons
    •Not well-studied in children
    •Interacts with a lot of common medications, such as warfarin (Coumadin) and antacids
    •Has many potentially serious side effects and risks (e.g., nerve issues, irregular heartbeat)

  • Common Side Effects of Pyrazinamide vs. Avelox

    Common Side Effects for
    •Mild joint or muscle ache
    •Nausea
    •Vomiting
    •Loss of appetite
    Common Side Effects for
    •Nausea (7%)
    •Diarrhea (6%)
    •Headache (4%)
    •Dizziness (3%)
    •Trouble sleeping (2%)
    •Vomiting (2%)
    •Constipation (2%)
    •Belly pain (2%)

  • Warnings of Pyrazinamide vs. Avelox

    Common Side Effects for
    •Liver injury
    •Gout
    •Caution in people with diabetes
    Common Side Effects for
    •Tendon inflammation and rupture
    •Effects on the brain, nerves, and mental health
    •Worsening of myasthenia gravis
    •Heart rhythm problems (QT prolongation)
    •Severe allergic and skin reactions
    •Severe damage to a major blood vessel
    •Severe infectious diarrhea
    •Changes in blood sugar
    •Sun and light sensitivity

  • Prices with our coupons for Pyrazinamide vs. Avelox

    Learn more about Pyrazinamide
    Learn more about Moxifloxacin

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