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Compare Isoniazid vs. Avelox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Isoniazid and moxifloxacin (Avelox) are both antibiotics used to treat infections, but they belong to different medication classes and treat different conditions. Isoniazid is an antimycobacterial agent primarily used for treating and preventing tuberculosis (TB), while moxifloxacin is a fluoroquinolone antibiotic used for various bacterial infections, including lung, skin, and sinus infections. Isoniazid is available as an oral tablet and solution, typically taken daily or a few times a week, and is often used with other TB medications to prevent resistance. Moxifloxacin is taken as an oral tablet once daily. Isoniazid can cause serious liver damage and interacts with many foods and medications, while moxifloxacin can cause tendon rupture, nerve damage, and heart rhythm problems. Both medications are available as generics, but they have different side effects and interactions. Isoniazid requires avoiding foods with tyramine and histamine, while moxifloxacin should not be taken with antacids or NSAIDs.

  • Isoniazid
    Moxifloxacin (Avelox)
  • Isoniazid
    Moxifloxacin (Avelox)

  • Summary of Isoniazid vs. Avelox

    Summary for Antimycobacterial agent
    Prescription only

    Isoniazid is an antimycobacterial agent for treating and preventing tuberculosis (TB) in children and adults. It's available as a generic oral tablet and solution, usually taken daily or a few times a week, depending on your dose. For treating active TB, you'll likely need to take it along with other TB medications (like rifampin, pyrazinamide, and ethambutol) to prevent antibiotic resistance. Serious side effects include severe liver injury. It's also known to interact with many foods and medications.

    Summary for Fluoroquinolone antibiotic
    Prescription only

    Moxifloxacin (Avelox) is a fluoroquinolone antibiotic. It can treat different types of infections, including certain skin infections and lung infections, in adults. But because moxifloxacin (Avelox) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when safer options aren't available. Moxifloxacin (Avelox) is taken by mouth, typically once daily. Some of the more common side effects of this medication include nausea, diarrhea, and headache. Moxifloxacin is generic only, brand-name Avelox is no longer available.

  • Indications of Isoniazid vs. Avelox

    Indications for
    •Tuberculosis (TB) infection
    •Prevention of TB if you're at high risk for infection
    Indications for

    Treatment of certain bacterial infections, including:

    •Lung infections (e.g., community acquired pneumonia, chronic bronchitis flare-ups)
    •Skin infections
    •Gut infections
    •Plague
    •Sinus infections

  • Pros and Cons of Isoniazid vs. Avelox

    Pros and Const for Antimycobacterial agent
    Pros
    •Is one of the main medications used to treat TB
    •Can be taken by itself for prevention of TB (along with a pyridoxine supplement)
    •Available as an oral tablet and oral solution
    •Available as a lower-cost generic
    Cons
    •Can cause serious liver damage
    •Likely will need to take it for many months
    •You might need to take each dose in front of a healthcare professional
    •Interacts with many foods and medications
    Pros and Const for Fluoroquinolone antibiotic
    Pros
    •Can take with or without food
    •Only taken once a day
    •Treats many types of infections
    •Might be an option for people who have penicillin allergy
    Cons
    •Not well-studied in children
    •Interacts with a lot of common medications, such as warfarin (Coumadin) and antacids
    •Has many potentially serious side effects and risks (e.g., nerve issues, irregular heartbeat)

  • Common Side Effects of Isoniazid vs. Avelox

    Common Side Effects for
    •Tingling or numbness in your hands and feet
    •Rise in liver enzymes
    Common Side Effects for
    •Nausea (7%)
    •Diarrhea (6%)
    •Headache (4%)
    •Dizziness (3%)
    •Trouble sleeping (2%)
    •Vomiting (2%)
    •Constipation (2%)
    •Belly pain (2%)

  • Warnings of Isoniazid vs. Avelox

    Common Side Effects for
    •Liver injury (hepatitis)
    •Interactions
    Common Side Effects for
    •Tendon inflammation and rupture
    •Effects on the brain, nerves, and mental health
    •Worsening of myasthenia gravis
    •Heart rhythm problems (QT prolongation)
    •Severe allergic and skin reactions
    •Severe damage to a major blood vessel
    •Severe infectious diarrhea
    •Changes in blood sugar
    •Sun and light sensitivity

  • Prices with our coupons for Isoniazid vs. Avelox

    Learn more about Isoniazid
    Learn more about Moxifloxacin

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