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Flagyl vs. Minocycline

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Metronidazole (Flagyl) and Minocycline (Minocin) are both antibiotics, but they belong to different classes and treat different types of infections. Metronidazole is a nitroimidazole antibiotic that treats bacterial and parasitic infections like bacterial vaginosis and trichomoniasis. It is taken orally, usually three times a day, and should not be mixed with alcohol due to serious interactions. Common side effects include diarrhea, nausea, and a metallic taste. Minocycline, on the other hand, is a tetracycline antibiotic used for bacterial infections such as UTIs, respiratory infections, and acne. It can be taken with or without food, but it makes you more sensitive to the sun and can stain children's teeth. Both medications are available as a lower-cost generic. Minocycline is not recommended during pregnancy and can interact with birth control pills and blood thinners. Both medications have serious side effects, but they differ in their specific risks and the types of infections they treat.

Metronidazole

(Flagyl)

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Minocycline

 

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Summary for Flagyl

Prescription only

Metronidazole (Flagyl) is an oral antibiotic for adults and children. It's used to treat certain bacterial and parasitic infections, including bacterial vaginosis (a type of vaginal bacteria infection) and trichomoniasis (a sexually transmitted infection, or STI). Metronidazole (Flagyl) is taken by mouth, typically 3 times a day. Some common side effects of this medication include diarrhea, nausea, and vomiting. Avoid drinking alcohol while taking and for 3 days after stopping metronidazole (Flagyl) because this combination can cause a serious reaction. Metronidazole (Flagyl) is available as a lower-cost generic.

Indications for Flagyl

Treatment of certain bacterial and parasitic infections, including:

Pros and Cons for Flagyl

Pros

  • Taken by mouth
  • Available as a lower-cost generic medication
  • Can be used to treat different types of bacterial infection
  • Immediate-release formulations can be taken with or without food

Cons

Common Side Effects for Flagyl

Please note: These are common side effects reported by people who took extended-release metronidazole (Flagyl)

  • Headache (18%)
  • Inflammation of the vagina (15%)
  • Nausea (10%)
  • Metallic taste (9%)
  • Flu-like symptoms (6%)

Warnings for Flagyl

  • Possible risk of cancer
  • Serious allergic reactions
  • Brain and nerve problems
  • Liver and kidney problems
  • Risk of fungal infection
  • Risk of drug resistance
  • Lower white blood cell counts
  • Interaction with other medications

Summary for Minocycline

Prescription only

Immediate-release minocycline is a tetracycline antibiotic used to treat many types of bacterial infections in adults and children 8 years and older. These include urinary tract infections (UTIs), sinus infections, and even severe acne. It comes as a tablet or capsule, and is usually taken by mouth every 12 hours. Common side effects include headache, tiredness, and dizziness.

Indications for Minocycline

Pros and Cons for Minocycline

Pros

  • Can take with or without food
  • Treats many different types of bacterial infections
  • A good alternative if you're allergic to penicillin
  • Taken twice a day

Cons

  • Can make your skin more sensitive to sunlight
  • Can stain children's teeth during tooth development
  • Interacts with blood thinners and birth control pills
  • Not safe in pregnancy or breastfeeding

Common Side Effects for Minocycline

Warnings for Minocycline

  • Harm to unborn babies
  • Tooth discoloration
  • Slow bone growth
  • Infectious diarrhea
  • Severe allergic and serious skin reactions
  • Kidney and liver damage
  • Brain and nerve effects
  • High pressure in the brain
  • Autoimmune problems
  • Sun sensitivity
  • Darkening of body tissues
  • New infection

Prices with our coupons for Flagyl vs. Minocycline

Price Card Drug Icon
Metronidazole14 tablets / 500mg
$10.73$14.75
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Price Card Drug Icon
Minocycline30 capsules / 100mg
$20.36$29.64
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