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Compare Mondoxyne NL vs. Malarone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Doxycycline monohydrate (brands: Monodox, Oracea, Vibramycin monohydrate) and Malarone (generic name: atovaquone/proguanil) are both prescription medications, but they serve different purposes. Doxycycline monohydrate is a tetracycline antibiotic used to treat a wide range of bacterial infections, including pneumonia, STIs, and severe acne, and it is also used for rosacea. In contrast, Malarone is an antimalarial medication used to prevent and treat malaria caused by Plasmodium falciparum. Doxycycline monohydrate is taken twice daily for most infections, while Malarone is taken once daily. Doxycycline monohydrate can cause tooth discoloration in children and is not safe during pregnancy, whereas Malarone is not recommended for people with severe kidney or liver problems and should not be used during pregnancy and breastfeeding. Additionally, doxycycline monohydrate can make your skin more sensitive to sunlight, while Malarone might cause vivid dreams and liver problems. Both medications are available in generic forms, making them more affordable options.

  • Doxycycline monohydrate
    Malarone (atovaquone / proguanil)
  • Doxycycline monohydrate
    Malarone (atovaquone / proguanil)

  • Summary of Mondoxyne NL vs. Malarone

    Summary for Tetracycline antibiotic
    Prescription only

    Doxycycline monohydrate is an antibiotic that treats many types of bacterial infections. It can be used in adults and children to treat infections, but it can sometimes cause tooth discoloration in children 8 years and younger. It's also used to treat rosacea.

    Summary for Antimalarial
    Prescription only

    Malarone (atovaquone / proguanil) is a CDC-recommended medication to help prevent and treat malaria. This combination medication is taken by mouth once per day. It doesn't have many side effects and can be used in children and adults.

  • Indications of Mondoxyne NL vs. Malarone

    Indications for

    Doxycycline monohydrate is used to treat many different infections caused by bacteria. Some examples include:

    •Lung infections (such as pneumonia)
    •Infections caused by ticks, mites, or fleas (Rocky Mountain spotted fever or typhus fever)
    •Sexually transmitted infections (STIs such as chlamydia, gonorrhea, or syphilis)
    •Urinary tract infections (UTIs)
    •Stomach infections
    •Severe acne
    •Anthrax
    •Plague
    •Cholera
    •Rosacea
    Indications for
    •Prevention and treatment of malaria caused by Plasmodium falciparum species

  • Pros and Cons of Mondoxyne NL vs. Malarone

    Pros and Const for Tetracycline antibiotic
    Pros
    •Available as a lower-cost generic medication
    •Available in multiple dosage strengths as both a capsule and tablet
    •Works well to treat a wide range of bacterial infections, including pneumonia and severe acne
    •First-choice treatment option for rosacea (Oracea only)
    •Good option if you're allergic to penicillin antibiotics
    Cons
    •Must take twice daily to treat most infections
    •Can make your skin more sensitive to sunlight and cause sunburn
    •Might cause tooth discoloration in children 8 years and younger
    •Oracea needs to be taken on an empty stomach
    •Might not be safe in pregnancy
    Pros and Const for Antimalarial
    Pros
    •Works well for preventing and treating malaria
    •Can use for traveling to areas known to have resistance to chloroquine, another antimalarial medication
    •Good choice for shorter trips because you only have to take it for 1 more week after leaving from the malaria area, rather than for 4 more weeks with other malaria medications (e.g., mefloquine, chloroquine)
    •Has relatively few side effects
    Cons
    •Not the best choice for people with severe kidney or liver problems
    •Not recommended for pregnant or breastfeeding females
    •Taken once per day (compared to other antimalarial medications that are taken once per week)

  • Common Side Effects of Mondoxyne NL vs. Malarone

    Common Side Effects for

    Doxycycline monohydrate (Monodox, Vibramycin):

    •Nausea
    •Vomiting
    •Stomach pain or discomfort
    •Diarrhea
    •Skin rash
    •Sensitivity to sunlight

    Oracea:

    •Nose and throat infection (5%)
    •Diarrhea (5%)
    •Sinus infection (3%)
    •High blood pressure (3%)
    •Stuffy nose (2%)
    •Fungal infection (2%)
    •Flu (2%)
    •Stomach pain (2%)
    •Anxiety (2%)
    •Pain (2%)
    Common Side Effects for
    •Stomach pain
    •Nausea
    •Vomiting
    •Diarrhea
    •Low appetite
    •Headache
    •Weakness
    •Dizziness

  • Warnings of Mondoxyne NL vs. Malarone

    Common Side Effects for
    •Permanent tooth discoloration
    •Severe diarrhea
    •High pressure in the brain (intracranial hypertension or pseudotumor cerebri)
    •Harm to unborn and young babies
    •Sunburn
    •Damage to the esophagus
    •Autoimmune problems
    •Skin color changes
    •New infections
    •Sulfite allergy
    Common Side Effects for
    •Worsening infection
    •Liver damage

  • Prices with our coupons for Mondoxyne NL vs. Malarone

    Learn more about Doxycycline monohydrate
    Learn more about Malarone

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