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Zyvox vs. Flagyl

Linezolid (Zyvox) is an oxazolidinone antibiotic that's used to treat adults and children with certain bacterial infections, such as pneumonia and skin infections. This antibiotic can help fight hard-to-treat infections caused by certain bacteria, such as MRSA and VRE. Linezolid (Zyvox) is available as a tablet, powder for suspension, and injection. It's typically taken every 8 or 12 hours. Some side effects include nausea, diarrhea, and headache. This antibiotic also has a rare but serious risk for serotonin syndrome from interactions with medications like antidepressants.

• Pneumonia
• Skin infections (e.g., cellulitis, foot infection related to diabetes)
• Vancomycin-resistant Enterococcus faecium (VRE) infections

Adults

• Diarrhea (8%)
• Nausea (7%)
• Headache (6%)

Children

• Diarrhea (11%)
• Vomiting (9%)
• Anemia (low red blood cell count; 6%)
• Low platelets (up to 5%)

• Low blood cell counts
• Nerve and eye damage
• Serotonin syndrome
• Diarrhea from Clostridioides difficile infection
• Buildup of lactic acid in the blood (lactic acidosis)
• Seizures
• Low blood sugar
• Low blood sodium levels
• Caution use in people with phenylketonuria (PKU) - powder for suspension form only

Metronidazole (Flagyl) is an oral antibiotic for adults and children. It's used to treat certain bacterial and parasitic infections, including bacterial vaginosis (a type of vaginal bacteria infection) and trichomoniasis (a sexually transmitted infection, or STI). Metronidazole (Flagyl) is taken by mouth, typically 3 times a day. Some common side effects of this medication include diarrhea, nausea, and vomiting. Avoid drinking alcohol while taking and for 3 days after stopping metronidazole (Flagyl) because this combination can cause a serious reaction. Metronidazole (Flagyl) is available as a lower-cost generic.

Treatment of certain bacterial and parasitic infections, including:

• Trichomoniasis
• Amebiasis (parasitic gut infection)
• Serious bacterial infections, such as:
  • Abdominal infection (including peritonitis)
  • Skin infections
  • Gynecological infections (including endometritis)
  • Bloodstream infection (septicemia)
  • Bone and joint infections
  • Central nervous system infections (meningitis)
  • Lung infections (lower respiratory tract infections)
  • Heart infection (endocarditis)

Please note: These are common side effects reported by people who took extended-release metronidazole (Flagyl)

• Headache (18%)
• Inflammation of the vagina (15%)
• Nausea (10%)
• Metallic taste (9%)
• Flu-like symptoms (6%)

• Possible risk of cancer
• Serious allergic reactions
• Brain and nerve problems
• Liver and kidney problems
• Risk of fungal infection
• Risk of drug resistance
• Lower white blood cell counts
• Interaction with other medications