Compare Malarone vs. Aralen

Malarone (atovaquone/proguanil) and chloroquine phosphate are both used to prevent and treat malaria, but they have some key differences. Malarone is a combination of two medications, atovaquone and proguanil, which work together to stop the malaria parasite from growing. It is taken once per day and is effective in areas with chloroquine-resistant malaria. Chloroquine, on the other hand, is a single medication that interferes with the parasite's growth processes and is taken weekly for prevention. Both medications have a generic form. Chloroquine can cause serious side effects like heart rhythm problems and vision changes, especially with long-term use. Malarone is not recommended for people with severe kidney or liver problems and is not the best choice for pregnant or breastfeeding women. In contrast, chloroquine is considered safe for use during pregnancy. Both medications require a prescription and should be taken exactly as directed by your healthcare provider.