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Keflex vs. Monurol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cephalexin (generic name) and Fosfomycin (brand name Monurol) are both antibiotics, but they have different uses and dosing schedules. Cephalexin is a cephalosporin antibiotic that treats a variety of bacterial infections, including respiratory, ear, skin, bone, urinary tract, and reproductive system infections. It is taken multiple times a day for 7 to 14 days. Fosfomycin, on the other hand, is specifically used to treat urinary tract infections (UTIs) in women and is taken as a single dose mixed with water. Cephalexin is available in generic forms like capsules, tablets, and liquid suspensions, while Fosfomycin is available as a brand name or generic powder that you mix with water. Cephalexin can cause side effects like nausea, vomiting, and diarrhea, whereas Fosfomycin can cause diarrhea, nausea, and headache. Both medications can cause serious allergic reactions and a type of infectious diarrhea called *C. difficile*-related diarrhea. However, Fosfomycin is noted for its convenience of a single dose and fewer drug interactions.

Cephalexin

 

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Fosfomycin

(Monurol)

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Summary for Keflex

Prescription only

Cephalexin, also commonly known as Keflex, is a cephalosporin antibiotic for people ages 1 year and older. It can treat many types of bacterial infections. This includes ear infections, skin infections like cellulitis, urinary tract infections (UTIs), and strep throat. Cephalexin comes as capsules, tablets, and a liquid suspension. It's taken by mouth 2 to 4 times per day. Side effects can include nausea, vomiting, and diarrhea. Cephalexin is a generic medication; its brand name Keflex is no longer available.

Indications for Keflex

Pros and Cons for Keflex

Pros

  • Treats several common types of bacterial infections
  • Okay for children as young as 1 year old to take
  • Available as a liquid for people who have trouble swallowing pills

Cons

  • Usually need to take a few times per day
  • Might not be able to take if you're allergic to penicillins or other cephalosporin antibiotics
  • Not recommended for the cold or flu (these are viral illnesses, not bacterial infections)

Common Side Effects for Keflex

  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain

Warnings for Keflex

  • Allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Seizures
  • Higher risk of bleeding
  • Possible development of drug-resistant bacteria

Summary for Monurol

Prescription only

Fosfomycin (also known by its brand name, Monurol) is an antibiotic that's used for treating urinary tract infections (UTIs) in women, including those who are pregnant. It's a powder that's mixed with water before it's taken by mouth. Fosfomycin (Monurol) is a convenient option because you only need to take one dose to treat your infection and it doesn't have many drug interactions. Side effects include diarrhea, nausea, and headache.

Indications for Monurol

Pros and Cons for Monurol

Pros

  • Works well at treating UTIs, including those caused by resistant bacteria that are hard to treat with other antibiotics
  • Only need to take one dose to treat a UTI
  • Can use if you have kidney or liver problems

Cons

  • Can cause diarrhea
  • Only used to treat UTIs that don't have complications
  • Hasn't been studied in children age 12 years and younger

Common Side Effects for Monurol

  • Diarrhea (9%)
  • Vaginal inflammation (pain, redness, swelling, warmth; 6%)
  • Nausea (4%)
  • Headache (4%)

Warnings for Monurol

  • Diarrhea from Clostridioides difficile infection

Prices with our coupons for Keflex vs. Monurol

Price Card Drug Icon
Cephalexin28 capsules / 500mg
$10.68$29.97
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Fosfomycin1 packet / 3g
$33.03$77.37
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