Key takeaways
Augmentin (amoxicillin/clavulanate) and penicillin V potassium (penicillin VK) are both antibiotics, but they differ in their composition and use. Augmentin combines amoxicillin with clavulanate, which helps fight bacteria that can resist amoxicillin alone, making it effective for a broader range of infections such as ear, sinus, respiratory, skin, and urinary tract infections. Penicillin VK, on the other hand, is used mainly for strep throat, scarlet fever, certain types of pneumonia, and staph skin infections. While Augmentin is taken two to three times daily, penicillin VK is usually taken every 6 to 8 hours. Both antibiotics can cause side effects like nausea and diarrhea, and neither should be used if you have a penicillin allergy. Augmentin is more versatile due to its combination formula, whereas penicillin VK is preferred for specific strep infections.
