Spectracef vs. Augmentin for Skin Infection and Bacterial Infection: Important Differences and Potential Risks.

Key takeaways

Cefditoren (Spectracef) and Augmentin (amoxicillin/clavulanate) are both antibiotics used to treat bacterial infections, but they belong to different medication classes. Cefditoren is a cephalosporin antibiotic, while Augmentin combines a penicillin antibiotic with a beta-lactamase inhibitor. Cefditoren was used for lung and throat infections but is no longer available in the U.S. Augmentin treats a wider range of infections, including ear, sinus, skin, and urinary tract infections, and is available in various forms like tablets and liquid suspensions. Augmentin is available as a lower-cost generic, whereas cefditoren is not available at all. Common side effects of Augmentin include diarrhea, nausea, and rash, while cefditoren's side effects are not detailed due to its discontinuation. Augmentin can interact with medications like warfarin, and you should avoid alcohol while taking it.

Cefditoren

(Spectracef)

Get free coupons

Augmentin

(amoxicillin / clavulanate)

Get free coupons

Summary for Spectracef

Discontinued

Cefditoren (Spectracef) is a cephalosporin antibiotic that treats bacterial infections of the lungs (bronchitis and pneumonia) and throat (strep throat and tonsillitis). It is no longer available in the U.S.

Pros and Cons for Spectracef

Pros

Cons

Summary for Augmentin

Prescription only

Augmentin (amoxicillin / clavulanate) is an antibiotic medication. It contains a penicillin and a beta-lactamase inhibitor. This antibiotic treats many types of bacterial infections, like urinary tract infection (UTI), sinus infection, and ear infection, among others. It fights infections by preventing bacteria from protecting themselves from harm. This medication comes as tablets, chewable tablets, and a suspension that are taken by mouth typically two to three times daily. It's approved for use in adults and children. Common side effects include diarrhea, nausea, and rash.

Indications for Augmentin

Pros and Cons for Augmentin

Pros

Treats many types of bacterial infections in children and adults
Available as a tablet, chewable tablet, and oral suspension
Available as a lower-cost generic
Safe to use while pregnant and while breastfeeding

Cons

Typically need to take 2 or 3 times daily
Might not be able to take this antibiotic if you've had a severe penicillin allergy
Can cause stomach side effects like nausea, vomiting, and diarrhea

Common Side Effects for Augmentin

Immediate-release tablets, chewable tablets, and suspension

Diarrhea or loose stools (9%)
Nausea (3%)
Skin rash (3%)

Extended-release tablets

Diarrhea (15%)
Vaginal yeast infection (3%)

Augmentin ES-600 (amoxicillin / clavulanate) suspension

Vomiting (7%)
Fever (6%)
Rash (6%)
Upper respiratory tract infection (e.g., common cold; 4%)
Diarrhea (4%)

Warnings for Augmentin

Severe allergic reactions and skin reactions
Liver problems
Diarrhea from Clostridioides difficile infection
Caution use in people with phenylketonuria (PKU) - for chewable tablets and suspension