•Only used once a day
•Typically only used for 3 days
•Applicator can be washed and reused for each insertion
•Can be inserted without using an applicator
•Vaginal application can be uncomfortable for some people
•Might cause vaginal yeast infections
•Can't use condoms, diaphragms, or tampons during and up to 3 days after treatment
•Recommended to use at bedtime to prevent medication from leaking