Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Botox Cosmetic (onabotulinumtoxinA) and Daxxify (daxibotulinumtoxinA) are both neuromuscular blockers used to temporarily improve the appearance of frown lines. They work by relaxing muscles to reduce wrinkles. However, they have some differences. Botox Cosmetic is specifically approved for frown lines, forehead lines, and crow's feet, while Daxxify is approved for frown lines and neck spasms (cervical dystonia). Botox Cosmetic is typically injected every 3 months, with effects lasting up to 4 months, whereas Daxxify can last up to 6 months or longer. Both medications are only available as injections given by a healthcare provider, but neither is available in a generic form. Common side effects for both include headache, drooping eyelids, injection site reactions and muscle weakness. Both medications carry risks of serious side effects if the toxin spreads beyond the injection site, so it's important to follow your provider's instructions carefully.
Botox cosmetic (onabotulinumtoxinA)
Daxxify
Botox cosmetic (onabotulinumtoxinA)
Daxxify
Summary of Botox Cosmetic vs. Daxxify
Summary for Neuromuscular blocker
Prescription only
Botox Cosmetic (onabotulinumtoxinA) is a prescription injection used in adults to temporarily improve the look of facial lines. It's FDA approved to treat moderate to severe frown lines between the eyebrows, forehead lines, crow’s feet, and neck lines. The medication is injected directly into the facial muscles by a trained healthcare professional. Side effects can vary depending on the injection site and can include headache and droopy eyelids.
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Botox Cosmetic (onabotulinumtoxinA) is different from medical Botox, which is used for certain health conditions like migraines or muscle spasms.
Summary for Neuromuscular blocker
Prescription only
Daxxify (daxibotulinumtoxinA or daxibotulinumtoxinA-lanm) is an FDA-approved medication for adults to temporarily improve the appearance of frown lines (wrinkles between your eyebrows and in your forehead). It's also used to treat cervical dystonia (muscle spasms in the neck). This medication is injected into the muscles by a trained healthcare provider. Common side effects include headache and pain at the injection site. Daxxify seems to last longer than other botulinum toxin injections (e.g., Botox).
Indications of Botox Cosmetic vs. Daxxify
Indications for
Temporarily improves the appearance of moderate to severe facial lines, including:
•Frown lines
•Crow's feet
•Forehead lines
•Neck lines
Indications for
•Temporary improvement in the appearance of moderate-to-severe frown lines (glabellar lines) in adults
•Neck spasms (cervical dystonia) in adults
Pros and Cons of Botox Cosmetic vs. Daxxify
Pros and Const for Neuromuscular blocker
Pros
•Can treat many facial and neck lines at the same time