Key takeaways
Renova (Tretinoin) and tetracycline (Sumycin) are both prescription medications, but they serve very different purposes. Renova is a topical cream used to lessen fine wrinkles on your face, while tetracycline is an oral antibiotic used to treat various bacterial infections, including respiratory and urinary tract infections, as well as severe acne. Renova is a retinoic acid derivative that helps the skin renew itself, whereas tetracycline works by preventing bacteria from growing. Renova is applied once daily in the evening and can cause skin irritation and increased sensitivity to sunlight. In contrast, tetracycline must be taken multiple times a day and can cause stomach side effects and teeth staining in young children. Both medications are not safe for use during pregnancy. While several forms of tretinoin are available as generics, Renova (which is 0.02% tretinoin) is only available as a brand name cream. Tetracycline is available as a generic.
