Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Renova (Tretinoin) and tetracycline (Sumycin) are both prescription medications, but they serve very different purposes. Renova is a topical cream used to lessen fine wrinkles on your face, while tetracycline is an oral antibiotic used to treat various bacterial infections, including respiratory and urinary tract infections, as well as severe acne. Renova is a retinoic acid derivative that helps the skin renew itself, whereas tetracycline works by preventing bacteria from growing. Renova is applied once daily in the evening and can cause skin irritation and increased sensitivity to sunlight. In contrast, tetracycline must be taken multiple times a day and can cause stomach side effects and teeth staining in young children. Both medications are not safe for use during pregnancy. While several forms of tretinoin are available as generics, Renova (which is 0.02% tretinoin) is only available as a brand name cream. Tetracycline is available as a generic.
Renova (tretinoin)
Tetracycline
Renova (tretinoin)
Tetracycline
Summary of Renova vs. Tetracycline
Summary for Retinoic acid derivative
Prescription only
Renova is a topical retinoid that contains tretinoin 0.02% cream. Renova (tretinoin) can ease fine facial wrinkles, in addition to the regular use of sunscreen and sun-protective clothing. But it won't help get rid of deep wrinkles or hyperpigmentation from years of sun damage. Renova (tretinoin) is applied to the face once daily in the evening. This medication commonly causes skin irritation and peeling as side effects. Renova is a prescription medication that's brand name only and not available as a generic.
Summary for Tetracycline antibiotic
Prescription only
Tetracycline is an antibiotic used to treat many types of bacterial infections, such as respiratory tract infections and urinary tract infections (UTIs). It's also sometimes used to fight acne-causing bacteria. Tetracycline is available as a lower-cost generic capsule that's safe for adults and children over 8 years of age to take. The dosage is taken multiple times a day. Tetracycline can cause unpleasant stomach side effects. There's also a risk of teeth staining in young children whose teeth are still growing.