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Compare Ubrelvy vs. Zolmitriptan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Ubrelvy (ubrogepant)
Zolmitriptan (Zomig)
Ubrelvy (ubrogepant)
Zolmitriptan (Zomig)

Summary of Ubrelvy vs. Zolmitriptan

Summary for Calcitonin gene-related peptide (CGRP) receptor blocker
Prescription only

Ubrelvy (ubrogepant) is used to treat sudden migraine attacks in adults. Your provider will decide the dosage (50 mg or 100 mg) based on how well you respond to the medication, if you have kidney or liver problems, or if you're taking a medication that interacts with Ubrelvy (ubrogepant). Side effects include nausea, sleepiness, and dry mouth.

Summary for Triptan
Prescription only

Zolmitriptan (Zomig) is used for the short-term treatment of migraines. You typically take just one dose when you have a migraine. Zolmitriptan (Zomig) can cause side effects like dizziness and chest, neck, or jaw pain. This medication is a tablet that you swallow. It also comes as an orally disintegrating tablet (ODT) and a nasal spray, which can be good options for people who have trouble swallowing pills during a migraine. Zolmitriptan (Zomig) is available by prescription only as a brand-name and generic medication; it's not found over the counter.

Indications of Ubrelvy vs. Zolmitriptan

Indications for
•Migraine attacks with or without aura in adults
Indications for
•Treatment of migraine

Pros and Cons of Ubrelvy vs. Zolmitriptan

Pros and Const for Calcitonin gene-related peptide (CGRP) receptor blocker
Pros
•Can be taken with or without food
•Can be used to treat sudden migraine attacks
•Good option when triptan medications, such as sumatriptan (Imitrex) or rizatriptan (Maxalt), haven't worked to treat your migraines
Cons
•Can't be used to prevent migraines
•Must wait at least 2 hours after the first dose to take a second dose
•Interacts with a lot of medications
•Takes 1 to 2 hours to work
Pros and Const for Triptan
Pros
•One of the first-choice options for adults to treat moderate or severe migraine
•Works within 2 hours after taking the dose
•Has ODT and nasal spray forms, so it's a good option for people who have trouble swallowing pills during a migraine
Cons
•Not used for other types of headaches
•Doesn't prevent migraines from happening
•Can worsen your headaches if you take the medication for more than 9 days in a month

Common Side Effects of Ubrelvy vs. Zolmitriptan

Common Side Effects for
•Nausea (2-4%)
•Sleepiness (2-3%)
•Dry mouth (1-2%)
Common Side Effects for

Tablets and orally disintegrating tablets

•Nausea (up to 9%)
•Dizziness (up to 8%)
•Pins and needles feeling in the arms or legs (up to 7%)
•Neck, throat, or jaw pain, tightness, or pressure (up to 7%)
•Sleepiness (up to 6%)
•Feeling warm or cold (up to 6%)
•Body weakness (up to 5%)
•Dry mouth (up to 5%)
•Chest pain, tightness, pressure, or heaviness (up to 3%)

Nasal spray

•Unusual taste (up to 17%)
•Dizziness (6%)
•Pins and needles feeling in your arms or legs (5%)
•Throat pain (4%)
•Feeling warm (4%)
•Dry mouth (3%)
•Body weakness (3%)

Warnings of Ubrelvy vs. Zolmitriptan

Common Side Effects for
•Severe allergic reactions
Common Side Effects for
•Heart attack and chest pain (angina)
•Irregular heart rhythm (arrhythmias)
•Stroke or other brain injury
•Blood vessel issues
•Serotonin syndrome
•High blood pressure
•Caution use in people with phenylketonuria (PKU) - for orally disintegrating tablet only

Prices with our coupons for Ubrelvy vs. Zolmitriptan

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