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Compare Reyvow vs. Maxalt

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Reyvow (lasmiditan) and Maxalt (rizatriptan) are both used to treat migraines, but they have some key differences. Reyvow (lasmiditan) is a serotonin agonist, while Maxalt (rizatriptan) is a triptan. Reyvow (lasmiditan) is only available as a brand-name medication, making it more expensive, whereas Maxalt (rizatriptan) is available in a lower-cost generic form. Reyvow (lasmiditan) is a controlled substance due to its potential for abuse, but Maxalt (rizatriptan) is not. Reyvow (lasmiditan) can cause significant dizziness and sleepiness, requiring you to avoid driving for at least 8 hours after taking it. Maxalt (rizatriptan) can also cause drowsiness but typically works faster, within 30 minutes. Additionally, Maxalt (rizatriptan) can be used by children ages 6 and older, while Reyvow (lasmiditan) is only approved for adults.

  • Reyvow (lasmiditan)
    Rizatriptan (Maxalt)
  • Reyvow (lasmiditan)
    Rizatriptan (Maxalt)

  • Summary of Reyvow vs. Maxalt

    Summary for Serotonin agonist
    Prescription only

    Reyvow, the brand name for lasmiditan, is a serotonin agonist. It's used to treat migraine with or without aura in adults. It comes as a tablet that's taken by mouth when you have a migraine. Many people feel pain relief within 2 hours. Common side effects include dizziness, sleepiness, and a "pins-and-needles" feeling. Reyvow (lasmiditan) is a controlled substance because of the risk of misuse. Currently, Reyvow (lasmiditan) is a brand-name medication only; there's no generic yet.

    Summary for Triptan
    Prescription only

    Rizatriptan (Maxalt) is used to treat migraines with or without aura in people ages 6 years and older. Rizatriptan (Maxalt) is available as a lower-cost generic tablet and an orally disintegrating tablet (ODT) that's placed on the tongue. Common side effects include dizziness, headache, and sleepiness. It can interact with antidepressants and other similar migraine medications.

  • Indications of Reyvow vs. Maxalt

    Indications for
    •Treatment of migraine attacks with or without aura in adults
    Indications for
    •Treatment of migraine attacks with or without aura in people ages 6 years and older

  • Pros and Cons of Reyvow vs. Maxalt

    Pros and Const for Serotonin agonist
    Pros
    •Starts to work to relieve migraine pain within 2 hours
    •Can take with or without food
    •Available in 3 different strengths
    Cons
    •Might not work as well as triptans
    •Need to wait at least 8 hours before driving or operating machinery after taking the medication because it affects how well you can stay alert
    •Not used to prevent migraines
    Pros and Const for Triptan
    Pros
    •First-choice option for treating migraines
    •Can be used by children ages 6 years and older
    •Orally disintegrating tablet (ODT) a possible option for people who have problems swallowing
    •Works within 30 minutes
    Cons
    •Can't use to prevent migraines
    •Is short-acting, so it might not last as long
    •Not clear if taking a second dose (adults only) is actually helpful
    •Your migraines can get worse if you use this medication too often.

  • Common Side Effects of Reyvow vs. Maxalt

    Common Side Effects for
    •Dizziness (up to 17%)
    •Numbness or tingling feeling (up to 9%)
    •Sleepiness (up to 7%)
    •Tiredness (up to 6%)
    Common Side Effects for
    •Dizziness (4-9%)
    •Sleepiness (4-8%)
    •Tiredness (4-7%)
    •Nausea (4-6%)

  • Warnings of Reyvow vs. Maxalt

    Common Side Effects for
    •Dizziness and sleepiness
    •Serotonin syndrome
    •Medication-overuse headache
    Common Side Effects for
    •Heart problems and high blood pressure
    •Stroke or other brain injury
    •Extreme narrowing of blood vessels
    •Taking too much rizatriptan (Maxalt)
    •Serotonin syndrome
    •Caution use in people with phenylketonuria (PKU) - orally disintegrating tablets only

  • Prices with our coupons for Reyvow vs. Maxalt

    Learn more about Reyvow
    Learn more about Rizatriptan

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