Reyvow (lasmiditan) and Zecuity (sumatriptan) are both used to treat migraines, but they have some key differences. Reyvow (lasmiditan) is a serotonin agonist taken orally and is only available as a brand-name medication, making it potentially expensive. It can relieve migraine pain within two hours but can cause dizziness and sleepiness, affecting your ability to drive. Reyvow is a controlled substance due to its potential for abuse. On the other hand, Zecuity (sumatriptan) was a topical patch that worked by tightening blood vessels in the brain to relieve migraines. However, it has been discontinued in the United States due to reports of skin burns and scarring. Unlike Reyvow, sumatriptan is available in other forms, such as tablets and nasal sprays, which your provider can recommend as alternatives.