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Compare Qulipta vs. Nurtec

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Atogepant (Qulipta) and rimegepant (Nurtec ODT) are both prescription medications used to prevent migraines in adults. They are both calcitonin gene-related peptide (CGRP) receptor blockers. However, they have some differences. Atogepant is only used for preventing migraines and is taken as a tablet once daily, while rimegepant can both prevent and treat migraines and is taken every other day for prevention or as needed for treatment. Both medications are only available in a branded version. Common side effects of atogepant include nausea, constipation, and sleepiness, while rimegepant may cause nausea and stomach pain. Both medications can cause serious allergic reactions and can interact with grapefruit juice. Both medications have many interactions, so be sure your prescriber and pharmacist have a complete list of all the medications you take.

  • Qulipta (atogepant)
    Nurtec odt (rimegepant)
  • Qulipta (atogepant)
    Nurtec odt (rimegepant)

  • Summary of Qulipta vs. Nurtec

    Summary for Calcitonin gene-related peptide (CGRP) receptor blocker
    Prescription only

    Qulipta (atogepant) is a medication that's used to prevent migraines in adults. The specific dosing will depend on how many migraines you have per month, but the medication is typically taken once daily. Qulipta (atogepant) is currently brand only; it isn't available as a lower-cost generic yet. Side effects include nausea, constipation, and sleepiness.

    Summary for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Prescription only

    Nurtec ODT (rimegepant) is a type of migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It helps treat migraine attacks with or without aura in adults. It can also help prevent migraines from happening in the long run. This medication is an orally disintegrating tablet (ODT). You put it on or under the tongue and let it dissolve. The dosage is 1 tablet each time. But how often you take the medication depends on if you're taking it to prevent or treat migraines. Side effects include nausea and stomach pain. Nurtec ODT (rimegepant) is a brand-name medication; there's no generic version yet.

  • Indications of Qulipta vs. Nurtec

    Indications for
    •Prevention of migraines in adults
    Indications for
    •Treatment of migraines with or without aura in adults
    •Prevention of migraines with or without aura in adults

  • Pros and Cons of Qulipta vs. Nurtec

    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor blocker
    Pros
    •Taken once per day
    •Can take with or without food
    •Can use if you have mild-to-moderate liver problems
    Cons
    •Not used for treating a migraine attack
    •Unknown whether it's safe or works well in children
    •Hasn't been studied in pregnant women
    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Pros
    •A first-choice option for preventing migraines
    •Generally has fewer side effects than triptans
    •Can take without any foods or liquids
    •Dissolves on the tongue, so it's a good option for people who don't like to or can't swallow pills
    Cons
    •Usually a second-choice option for treating migraines (after trying triptans)
    •Can interact with certain medications, like some antifungals and antiseizure medications
    •Might not be the best choice if you have serious liver or kidney problems
    •Not approved for children (but studies are ongoing)

  • Common Side Effects of Qulipta vs. Nurtec

    Common Side Effects for
    •Nausea (5-9%)
    •Constipation (6-8%)
    •Fatigue or sleepiness (4-5%)
    Common Side Effects for
    •Nausea (up to 3%)
    •Stomach pain or indigestion (up to 2%)

  • Warnings of Qulipta vs. Nurtec

    Common Side Effects for
    •Allergic reactions
    Common Side Effects for
    •Allergic reactions
    •High blood pressure
    •Raynaud's phenomenon

  • Prices with our coupons for Qulipta vs. Nurtec

    Learn more about Qulipta
    Learn more about Nurtec odt

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