Key takeaways
Atogepant (Qulipta) and rimegepant (Nurtec ODT) are both prescription medications used to prevent migraines in adults. They are both calcitonin gene-related peptide (CGRP) receptor blockers. However, they have some differences. Atogepant is only used for preventing migraines and is taken as a tablet once daily, while rimegepant can both prevent and treat migraines and is taken every other day for prevention or as needed for treatment. Both medications are only available in a branded version. Common side effects of atogepant include nausea, constipation, and sleepiness, while rimegepant may cause nausea and stomach pain. Both medications can cause serious allergic reactions and can interact with grapefruit juice. Both medications have many interactions, so be sure your prescriber and pharmacist have a complete list of all the medications you take.
