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Compare Emgality vs. Frova

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Emgality (galcanezumab) and Frova (frovatriptan) are both used to manage migraines, but they work differently and are used in different ways. Emgality is a monoclonal antibody that prevents migraines and treats cluster headaches by blocking a protein called calcitonin-gene related peptide (CGRP). It's given as a monthly injection under the skin. On the other hand, Frova is a triptan that treats migraines by tightening blood vessels in the brain and stopping pain-causing chemicals. It's taken as a pill when you feel a migraine coming on and can be taken again after two hours if needed. Emgality is not available in a generic form, while Frova is available as a lower-cost generic. Emgality is used for prevention, while Frova is for short-term treatment. Emgality's common side effects include injection site reactions, while Frova can cause dizziness and tiredness.

  • Emgality (galcanezumab)
    Frovatriptan (Frova)
  • Emgality (galcanezumab)
    Frovatriptan (Frova)

  • Summary of Emgality vs. Frova

    Summary for CGRP antagonist
    Prescription only

    Emgality (galcanezumab or galcanezumab-gnlm) is an injectable medication that can help prevent migraine attacks in adults. It can also help treat cluster headaches in adults. This medication is a monoclonal antibody that works as a CGRP antagonist. It blocks the CGRP protein in the brain that can cause migraine and headache pain. Emgality (galcanezumab) comes as a prefilled pen and syringe. You inject one dose of the medication under the skin monthly. Some common side effects include pain, itching, and redness at the injection site.

    Summary for Triptan
    Prescription only

    Frovatriptan (Frova) is one of the many triptans available for treating migraine. It's approved for adults who have migraines with or without aura. The dosage is a tablet that's swallowed whole when you have a migraine. You can take another tablet 2 hours later if the medication doesn't completely relieve your migraine. Side effects include dizziness, tiredness, and sometimes chest tightness. Frovatriptan (Frova) is available as a brand-name and generic medication.

  • Indications of Emgality vs. Frova

    Indications for
    •Prevention of migraines in adults
    •Treatment of episodic (occasional) cluster headaches in adults
    Indications for
    •Treatment of migraine with or without aura in adults

  • Pros and Cons of Emgality vs. Frova

    Pros and Const for CGRP antagonist
    Pros
    •Only needs to be given once a month
    •Good option for people who have a hard time taking medications by mouth
    •Generally well tolerated
    Cons
    •Not a good option for people who don't like needles
    •Need to store in a refrigerator
    •Not known if the medication works well or is safe in children, during pregnancy, or while breastfeeding
    Pros and Const for Triptan
    Pros
    •A first-choice option for short-term treatment of migraines
    •Effects might last longer than other triptans
    Cons
    •Might not be a good option for people who have trouble swallowing pills whole during a migraine
    •Might take about 2 hours or longer to feel complete pain relief
    •Not recommended for children under 18 years old

  • Common Side Effects of Emgality vs. Frova

    Common Side Effects for
    •Pain, itching, warmth, and other injection site reactions (18%)
    Common Side Effects for
    •Dizziness (8%)
    •Tiredness (5%)
    •Headache (4%)
    •"Pins and needles" feeling in the hands or legs (4%)
    •Flushing (4%)
    •Dry mouth (3%)
    •Hot or cold sensation (3%)
    •Bone pain (3%)
    •Indigestion (2%)
    •Chest pain (2%)

  • Warnings of Emgality vs. Frova

    Common Side Effects for
    •Serious allergic reactions
    •High blood pressure
    •Raynaud's phenomenon
    Common Side Effects for
    •Heart attack and chest pain (angina)
    •Irregular heart rhythm (arrhythmias)
    •Stroke or other brain injury
    •Extreme narrowing of blood vessels
    •Worse headaches if you take frovatriptan (Frova) too often
    •Serotonin syndrome
    •High blood pressure
    •Allergic reaction

  • Prices with our coupons for Emgality vs. Frova

    Learn more about Emgality
    Learn more about Frovatriptan

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